Negative modulation of SA signaling components by the capsid protein of tobacco mosaic virus is required for viral long-distance movement.
Plant J
; 106(4): 896-912, 2021 05.
Article
en En
| MEDLINE
| ID: mdl-33837606
ABSTRACT
An important aspect of plant-virus interaction is the way viruses dynamically move over long distances and how plant immunity modulates viral systemic movement. Salicylic acid (SA), a well-characterized hormone responsible for immune responses against virus, is activated through different transcription factors including TGA and WRKY. In tobamoviruses, evidence suggests that capsid protein (CP) is required for long-distance movement, although its precise role has not been fully characterized yet. Previously, we showed that the CP of Tobacco Mosaic Virus (TMV)-Cg negatively modulates the SA-mediated defense. In this study, we analyzed the impact of SA-defense mechanism on the long-distance transport of a truncated version of TMV (TMV ∆CP virus) that cannot move to systemic tissues. The study showed that the negative modulation of NPR1 and TGA10 factors allows the long-distance transport of TMV ∆CP virus. Moreover, we observed that the stabilization of DELLA proteins promotes TMV ∆CP systemic movement. We also characterized a group of genes, part of a network modulated by CP, involved in TMV ∆CP long-distance transport. Altogether, our results indicate that CP-mediated downregulation of SA signaling pathway is required for the virus systemic movement, and this role of CP may be linked to its ability to stabilize DELLA proteins.
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Texto completo:
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Banco de datos:
MEDLINE
Asunto principal:
Enfermedades de las Plantas
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Nicotiana
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Virus del Mosaico del Tabaco
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Transducción de Señal
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Ácido Salicílico
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Proteínas de la Cápside
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Interacciones Huésped-Patógeno
Idioma:
En
Año:
2021
Tipo del documento:
Article