Thiazolidinediones: An In-Depth Study of Their Synthesis and Application to Medicinal Chemistry in the Treatment of Diabetes Mellitus.

Long, Nathan; Le Gresley, Adam; Wren, Stephen P

Long, Nathan; Le Gresley, Adam; Wren, Stephen P.

Long N; Department of Chemical & Pharmaceutical Sciences, Faculty of Science, Engineering & Computing, Kingston University London, Penrhyn Road, Surrey, KT1 2EE, UK.
Le Gresley A; Department of Chemical & Pharmaceutical Sciences, Faculty of Science, Engineering & Computing, Kingston University London, Penrhyn Road, Surrey, KT1 2EE, UK.
Wren SP; Department of Chemical & Pharmaceutical Sciences, Faculty of Science, Engineering & Computing, Kingston University London, Penrhyn Road, Surrey, KT1 2EE, UK.

ChemMedChem ; 16(11): 1716-1735, 2021 06 07.

Article en En | MEDLINE | ID: mdl-33844475

Asunto(s)

Diabetes Mellitus/tratamiento farmacológico; Hipoglucemiantes/uso terapéutico; Tiazolidinedionas/uso terapéutico; Aldehído Reductasa/antagonistas & inhibidores; Aldehído Reductasa/metabolismo; Animales; Química Farmacéutica; Diabetes Mellitus/metabolismo; Humanos; Hipoglucemiantes/síntesis química; Hipoglucemiantes/química; PPAR gamma/antagonistas & inhibidores; PPAR gamma/metabolismo; Proteína Tirosina Fosfatasa no Receptora Tipo 1/antagonistas & inhibidores; Proteína Tirosina Fosfatasa no Receptora Tipo 1/metabolismo; Tiazolidinedionas/síntesis química; Tiazolidinedionas/química

Palabras clave

ALR2; Diabetes Mellitus; PPARÎ³; PTP1B; Thiazolidinediones

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tiazolidinedionas / Diabetes Mellitus / Hipoglucemiantes Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article

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