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Olinciguat, a stimulator of soluble guanylyl cyclase, attenuates inflammation, vaso-occlusion and nephropathy in mouse models of sickle cell disease.
Tchernychev, Boris; Li, Huihui; Lee, Sung-Kyun; Gao, Xin; Ramanarasimhaiah, Raghunath; Liu, Guang; Hall, Katherine C; Bernier, Sylvie G; Jones, Juli E; Feil, Susanne; Feil, Robert; Buys, Emmanuel S; Graul, Regina M; Frenette, Paul S; Masferrer, Jaime L.
  • Tchernychev B; Cyclerion Therapeutics Inc., Boston, Massachusetts, USA.
  • Li H; Departments of Medicine and Cell Biology, Albert Einstein College of Medicine, New York, New York, USA.
  • Lee SK; Departments of Medicine and Cell Biology, Albert Einstein College of Medicine, New York, New York, USA.
  • Gao X; Departments of Medicine and Cell Biology, Albert Einstein College of Medicine, New York, New York, USA.
  • Ramanarasimhaiah R; Cyclerion Therapeutics Inc., Boston, Massachusetts, USA.
  • Liu G; Cyclerion Therapeutics Inc., Boston, Massachusetts, USA.
  • Hall KC; Cyclerion Therapeutics Inc., Boston, Massachusetts, USA.
  • Bernier SG; Cyclerion Therapeutics Inc., Boston, Massachusetts, USA.
  • Jones JE; Cyclerion Therapeutics Inc., Boston, Massachusetts, USA.
  • Feil S; Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.
  • Feil R; Interfaculty Institute of Biochemistry, University of Tübingen, Tübingen, Germany.
  • Buys ES; Cyclerion Therapeutics Inc., Boston, Massachusetts, USA.
  • Graul RM; Cyclerion Therapeutics Inc., Boston, Massachusetts, USA.
  • Frenette PS; Departments of Medicine and Cell Biology, Albert Einstein College of Medicine, New York, New York, USA.
  • Masferrer JL; Cyclerion Therapeutics Inc., Boston, Massachusetts, USA.
Br J Pharmacol ; 178(17): 3463-3475, 2021 09.
Article en En | MEDLINE | ID: mdl-33864386

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Vasculares / Anemia de Células Falciformes Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Vasculares / Anemia de Células Falciformes Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article