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High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors.
Zhao, Yao; Du, Xiaoyu; Duan, Yinkai; Pan, Xiaoyan; Sun, Yifang; You, Tian; Han, Lin; Jin, Zhenming; Shang, Weijuan; Yu, Jing; Guo, Hangtian; Liu, Qianying; Wu, Yan; Peng, Chao; Wang, Jun; Zhu, Chenghao; Yang, Xiuna; Yang, Kailin; Lei, Ying; Guddat, Luke W; Xu, Wenqing; Xiao, Gengfu; Sun, Lei; Zhang, Leike; Rao, Zihe; Yang, Haitao.
  • Zhao Y; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Du X; Laboratory of Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing, 100091, China.
  • Duan Y; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Pan X; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China.
  • Sun Y; The Fifth People's Hospital of Shanghai, Fudan University and Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.
  • You T; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Han L; The Fifth People's Hospital of Shanghai, Fudan University and Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.
  • Jin Z; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Shang W; Laboratory of Structural Biology, School of Life Sciences and School of Medicine, Tsinghua University, Beijing, 100091, China.
  • Yu J; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China.
  • Guo H; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Liu Q; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Wu Y; The Fifth People's Hospital of Shanghai, Fudan University and Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China.
  • Peng C; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China.
  • Wang J; Zhangjiang Lab, National Facility for Protein Science in Shanghai, Shanghai Advanced Research Institute, Chinese Academy of Science, Shanghai, 201210, China.
  • Zhu C; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Yang X; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Yang K; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Lei Y; Taussig Cancer Center, Cleveland Clinic, Cleveland, OH, 44195, USA.
  • Guddat LW; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Xu W; School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Queensland, 4072, Australia.
  • Xiao G; Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.
  • Sun L; Zhangjiang Lab, National Facility for Protein Science in Shanghai, Shanghai Advanced Research Institute, Chinese Academy of Science, Shanghai, 201210, China.
  • Zhang L; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China.
  • Rao Z; The Fifth People's Hospital of Shanghai, Fudan University and Shanghai Key Laboratory of Medical Epigenetics, Institutes of Biomedical Sciences, Fudan University, Shanghai, 200032, China. llsun@fudan.edu.cn.
  • Yang H; State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, 430071, China. zhangleike@wh.iov.cn.
Protein Cell ; 12(11): 877-888, 2021 11.
Article en En | MEDLINE | ID: mdl-33864621
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteasas / Ensayos Analíticos de Alto Rendimiento / Proteasas Similares a la Papaína de Coronavirus Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Inhibidores de Proteasas / Ensayos Analíticos de Alto Rendimiento / Proteasas Similares a la Papaína de Coronavirus Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article