OMERACT consensus-based operational definition of contextual factors in rheumatology clinical trials: A mixed methods study.
Semin Arthritis Rheum
; 51(3): 601-606, 2021 06.
Article
en En
| MEDLINE
| ID: mdl-33875246
ABSTRACT
OBJECTIVES:
To develop an operational definition of contextual factors (CF) [1].METHODS:
Based on previously conducted interviews, we presented three CF types in a Delphi survey; Effect Modifying -, Outcome Influencing - and Measurement Affecting CFs. Subsequently, a virtual Special Interest Group (SIG) session was held for in depth discussion of Effect Modifying CFs.RESULTS:
Of 161 Delphi participants, 129 (80%) completed both rounds. After two rounds, we reached consensus (≥70% agreeing) for all but two statements. The 45 SIG participants were broadly supportive.CONCLUSION:
Through consensus we developed an operational definition of CFs, which was well received by OMERACT members.Palabras clave
Texto completo:
1
Ejes tematicos:
Pesquisa_clinica
Banco de datos:
MEDLINE
Asunto principal:
Reumatología
Tipo de estudio:
Guideline
/
Qualitative_research
Límite:
Humans
Idioma:
En
Año:
2021
Tipo del documento:
Article