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Pharmacological and cell-specific genetic PI3Kα inhibition worsens cardiac remodeling after myocardial infarction.
Chen, Xueyi; Zhabyeyev, Pavel; Azad, Abul K; Vanhaesebroeck, Bart; Grueter, Chad E; Murray, Allan G; Kassiri, Zamaneh; Oudit, Gavin Y.
  • Chen X; Department of Medicine, University of Alberta, Edmonton, Canada; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.
  • Zhabyeyev P; Department of Medicine, University of Alberta, Edmonton, Canada; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.
  • Azad AK; Department of Medicine, University of Alberta, Edmonton, Canada.
  • Vanhaesebroeck B; Cancer Institute, University College London, London, UK.
  • Grueter CE; Division of Cardiovascular Medicine, Department of Internal Medicine, Francois M. Abboud Cardiovascular Research Center, Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA.
  • Murray AG; Department of Medicine, University of Alberta, Edmonton, Canada.
  • Kassiri Z; Department of Physiology, University of Alberta, Edmonton, Canada; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada.
  • Oudit GY; Department of Medicine, University of Alberta, Edmonton, Canada; Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada. Electronic address: gavin.oudit@ualberta.ca.
J Mol Cell Cardiol ; 157: 17-30, 2021 08.
Article en En | MEDLINE | ID: mdl-33887328
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Remodelación Ventricular / Silenciador del Gen / Fosfatidilinositol 3-Quinasa Clase I / Inhibidores de las Quinasa Fosfoinosítidos-3 / Infarto del Miocardio Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Remodelación Ventricular / Silenciador del Gen / Fosfatidilinositol 3-Quinasa Clase I / Inhibidores de las Quinasa Fosfoinosítidos-3 / Infarto del Miocardio Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article