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Fc-GDF15 glyco-engineering and receptor binding affinity optimization for body weight regulation.
Fung, Ella; Kang, Liya; Sapashnik, Diana; Benard, Susan; Sievers, Annette; Liu, Yan; Yan, Guoying; Zhou, Jing; Rodriguez, Linette; Ma, Weijun; Stochaj, Wayne R; LaVallie, Edward; Wroblewska, Liliana; Kelleher, Kerry; Tam, Amy; Bezy, Olivier; Breen, Danna; Chabot, Jeffrey R; He, Tao; Lin, Laura; Wu, Zhidan; Mosyak, Lidia.
  • Fung E; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Kang L; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Sapashnik D; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Benard S; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Sievers A; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Liu Y; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Yan G; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Zhou J; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Rodriguez L; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Ma W; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Stochaj WR; Sanofi Research and Development, Sanofi North America, Framingham, MA, USA.
  • LaVallie E; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Wroblewska L; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Kelleher K; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Tam A; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Bezy O; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Breen D; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Chabot JR; Cellarity, Cambridge, MA, USA.
  • He T; Internal Medicine Research Unit, Pfizer Inc., 1 Portland Street, Cambridge, MA, USA.
  • Lin L; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Wu Z; BioMedicine Design, Pfizer Inc., 610 N Main Street, Cambridge, MA, USA.
  • Mosyak L; JOINN Biologics US Inc, Richmond, CA, USA.
Sci Rep ; 11(1): 8921, 2021 04 26.
Article en En | MEDLINE | ID: mdl-33903632
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Recombinantes de Fusión / Fragmentos Fc de Inmunoglobulinas / Pérdida de Peso / Receptores del Factor Neurotrófico Derivado de la Línea Celular Glial / Factor 15 de Diferenciación de Crecimiento Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas Recombinantes de Fusión / Fragmentos Fc de Inmunoglobulinas / Pérdida de Peso / Receptores del Factor Neurotrófico Derivado de la Línea Celular Glial / Factor 15 de Diferenciación de Crecimiento Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article