Predictive ability of a drug-based score in patients with advanced non-small-cell lung cancer receiving first-line immunotherapy.

Buti, Sebastiano; Bersanelli, Melissa; Perrone, Fabiana; Bracarda, Sergio; Di Maio, Massimo; Giusti, Raffaele; Nigro, Olga; Cortinovis, Diego L; Aerts, Joachim G J V; Guaitoli, Giorgia; Barbieri, Fausto; Ferrara, Miriam G; Bria, Emilio; Grossi, Francesco; Bareggi, Claudia; Berardi, Rossana; Torniai, Mariangela; Cantini, Luca; Sforza, Vincenzo; Genova, Carlo; Chiari, Rita; Rocco, Danilo; Della Gravara, Luigi; Gori, Stefania; De Tursi, Michele; Di Marino, Pietro; Mansueto, Giovanni; Zoratto, Federica; Filetti, Marco; Citarella, Fabrizio; Russano, Marco; Mazzoni, Francesca; Garassino, Marina C; De Toma, Alessandro; Signorelli, Diego; Gelibter, Alain; Siringo, Marco; Follador, Alessandro; Bisonni, Renato; Tuzi, Alessandro; Minuti, Gabriele; Landi, Lorenza; Ricciardi, Serena; Migliorino, Maria R; Tabbò, Fabrizio; Olmetto, Emanuela; Metro, Giulio; Adamo, Vincenzo; Russo, Alessandro; Spinelli, Gian P

Buti, Sebastiano; Bersanelli, Melissa; Perrone, Fabiana; Bracarda, Sergio; Di Maio, Massimo; Giusti, Raffaele; Nigro, Olga; Cortinovis, Diego L; Aerts, Joachim G J V; Guaitoli, Giorgia; Barbieri, Fausto; Ferrara, Miriam G; Bria, Emilio; Grossi, Francesco; Bareggi, Claudia; Berardi, Rossana; Torniai, Mariangela; Cantini, Luca; Sforza, Vincenzo; Genova, Carlo; Chiari, Rita; Rocco, Danilo; Della Gravara, Luigi; Gori, Stefania; De Tursi, Michele; Di Marino, Pietro; Mansueto, Giovanni; Zoratto, Federica; Filetti, Marco; Citarella, Fabrizio; Russano, Marco; Mazzoni, Francesca; Garassino, Marina C; De Toma, Alessandro; Signorelli, Diego; Gelibter, Alain; Siringo, Marco; Follador, Alessandro; Bisonni, Renato; Tuzi, Alessandro; Minuti, Gabriele; Landi, Lorenza; Ricciardi, Serena; Migliorino, Maria R; Tabbò, Fabrizio; Olmetto, Emanuela; Metro, Giulio; Adamo, Vincenzo; Russo, Alessandro; Spinelli, Gian P.

Buti S; Medical Oncology Unit, University Hospital of Parma, Parma, Italy.
Bersanelli M; Medical Oncology Unit, University Hospital of Parma, Parma, Italy.
Perrone F; Medical Oncology Unit, University Hospital of Parma, Parma, Italy.
Bracarda S; Struttura Complessa di Oncologia Medica e Traslazionale, Azienda Ospedaliera Santa Maria di Terni, Italy.
Di Maio M; Department of Oncology, University of Turin and Medical Oncology, AO Ordine Mauriziano, Turin, Italy.
Giusti R; Medical Oncolgy, St. Andrea Hospital, Rome, Italy.
Nigro O; Medical Oncology, ASST-Sette Laghi, Varese, Italy.
Cortinovis DL; Medical Oncology, Ospedale San Gerardo, Monza, Italy.
Aerts JGJV; Department of Pulmonary Diseases, Erasmus Medical Center, Rotterdam, the Netherlands.
Guaitoli G; Dipartimeto di Oncologia Ed Ematologia, AOU Policlinico Modena, Modena, Italy.
Barbieri F; Dipartimeto di Oncologia Ed Ematologia, AOU Policlinico Modena, Modena, Italy.
Ferrara MG; Comprehensive Cancer Center, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy; Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Lazio, Italy.
Bria E; Comprehensive Cancer Center, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy; Department of Translational Medicine and Surgery, Università Cattolica del Sacro Cuore, Rome, Lazio, Italy.
Grossi F; Division of Medical Oncology, University of Insubria, Varese, Italy.
Bareggi C; Medical Oncology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Berardi R; Oncology Clinic, Università Politecnica Delle Marche, Ospedali Riuniti Di Ancona, Ancona, Italy.
Torniai M; Oncology Clinic, Università Politecnica Delle Marche, Ospedali Riuniti Di Ancona, Ancona, Italy.
Cantini L; Department of Pulmonary Diseases, Erasmus Medical Center, Rotterdam, the Netherlands; Oncology Clinic, Università Politecnica Delle Marche, Ospedali Riuniti Di Ancona, Ancona, Italy.
Sforza V; Thoracic Medical Oncology, Istituto Nazionale Tumori "Fondazione G Pascale", IRCCS, Napoli, Italy.
Genova C; Lung Cancer Unit IRCCS Ospedale Policlinico San Martino, Genova, Italy.
Chiari R; Medical Oncology, Ospedali Riuniti Padova Sud "Madre Teresa Di Calcutta", Monselice, Italy.
Rocco D; Pneumo-Oncology Unit, Monaldi Hospital, Naples, Italy.
Della Gravara L; Pneumo-Oncology Unit, Monaldi Hospital, Naples, Italy.
Gori S; Oncology Unit, IRCCS Ospedale Sacro Cuore Don Calabria, Negrar, VR, Italy.
De Tursi M; Dipartimento di Terapie Innovative in Medicina e Odontoiatria, Università G. D'Annunzio, Chieti-Pescara, Chieti, Italy.
Di Marino P; Clinical Oncology Unit, S.S. Annunziata Hospital, Chieti, Italy.
Mansueto G; Medical Oncology, F. Spaziani Hospital, Frosinone, Italy.
Zoratto F; Medical Oncology, Santa Maria Goretti Hospital, Latina, Italy.
Filetti M; Medical Oncolgy, St. Andrea Hospital, Rome, Italy.
Citarella F; Medical Oncology, Campus Bio-Medico University, Rome, Italy.
Russano M; Medical Oncology, Campus Bio-Medico University, Rome, Italy.
Mazzoni F; Department of Oncology, Careggi University Hospital, Florence, Italy.
Garassino MC; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
De Toma A; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy.
Signorelli D; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy; Niguarda Cancer Center, Grande Ospedale Metropolitano Niguarda, Milan, Italy.
Gelibter A; Medical Oncology (B), Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
Siringo M; Medical Oncology (B), Policlinico Umberto I, "Sapienza" University of Rome, Rome, Italy.
Follador A; Department of Oncology, University Hospital Santa Maria Della Misericordia, Udine, Italy.
Bisonni R; Medical Oncology, Fermo Area Vasta 4, Fermo, Italy.
Tuzi A; Medical Oncology, ASST-Sette Laghi, Varese, Italy.
Minuti G; Department of Oncology and Hematology, AUSL Romagna, Ravenna, Italy.
Landi L; Department of Oncology and Hematology, AUSL Romagna, Ravenna, Italy.
Ricciardi S; Pneumo-Oncology Unit, St. Camillo-Forlanini Hospital, Rome, Italy.
Migliorino MR; Pneumo-Oncology Unit, St. Camillo-Forlanini Hospital, Rome, Italy.
Tabbò F; Department of Oncology, University of Turin, San Luigi Hospital, Orbassano, (TO), Italy.
Olmetto E; Department of Oncology, University of Turin, San Luigi Hospital, Orbassano, (TO), Italy.
Metro G; Department of Medical Oncology, Santa Maria Della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.
Adamo V; Medical Oncology, A.O. Papardo & Department of Human Pathology, University of Messina, Italy.
Russo A; Medical Oncology, A.O. Papardo & Department of Human Pathology, University of Messina, Italy.
Spinelli GP; UOC Territorial Oncology of Aprilia, AUSL Latina, University of Rome Sapienza, Aprilia, Italy.

Eur J Cancer ; 150: 224-231, 2021 06.

Article en En | MEDLINE | ID: mdl-33934059

Asunto(s)

Corticoesteroides/uso terapéutico; Antibacterianos/uso terapéutico; Anticuerpos Monoclonales Humanizados/uso terapéutico; Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico; Técnicas de Apoyo para la Decisión; Inhibidores de Puntos de Control Inmunológico/uso terapéutico; Inmunoterapia; Neoplasias Pulmonares/tratamiento farmacológico; Corticoesteroides/efectos adversos; Anciano; Antibacterianos/efectos adversos; Anticuerpos Monoclonales Humanizados/efectos adversos; Carcinoma de Pulmón de Células no Pequeñas/inmunología; Carcinoma de Pulmón de Células no Pequeñas/mortalidad; Carcinoma de Pulmón de Células no Pequeñas/patología; Toma de Decisiones Clínicas; Interacciones Farmacológicas; Femenino; Humanos; Inhibidores de Puntos de Control Inmunológico/efectos adversos; Inmunoterapia/efectos adversos; Italia; Neoplasias Pulmonares/inmunología; Neoplasias Pulmonares/mortalidad; Neoplasias Pulmonares/patología; Masculino; Selección de Paciente; Polifarmacia; Valor Predictivo de las Pruebas; Supervivencia sin Progresión; Inhibidores de la Bomba de Protones/efectos adversos; Inhibidores de la Bomba de Protones/uso terapéutico; Reproducibilidad de los Resultados; Estudios Retrospectivos; Medición de Riesgo; Factores de Riesgo

Palabras clave

Concomitant medications; First-line; Immunotherapy; Nonsmall-cell lung cancer; Pembrolizumab; Predictive score

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Técnicas de Apoyo para la Decisión / Corticoesteroides / Carcinoma de Pulmón de Células no Pequeñas / Anticuerpos Monoclonales Humanizados / Inhibidores de Puntos de Control Inmunológico / Inmunoterapia / Neoplasias Pulmonares / Antibacterianos Tipo de estudio: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Aged / Female / Humans / Male País como asunto: Europa Idioma: En Año: 2021 Tipo del documento: Article

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