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Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate.
Li, Wan Hua; Huang, Ke; Cai, Yang; Wang, Qian Wen; Zhu, Wen Jie; Hou, Yun Nan; Wang, Sujing; Cao, Sheng; Zhao, Zhi Ying; Xie, Xu Jie; Du, Yang; Lee, Chi-Sing; Lee, Hon Cheung; Zhang, Hongmin; Zhao, Yong Juan.
  • Li WH; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Huang K; Ciechanover Institute of Precision and Regenerative Medicine, School of Life and Health Sciences, The Chinese University of Hong Kong, Shenzhen, China.
  • Cai Y; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
  • Wang QW; Department of Biology, Southern University of Science and Technology, Shenzhen, China.
  • Zhu WJ; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Hou YN; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Wang S; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Cao S; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Zhao ZY; Kobilka Institute of Innovative Drug Discovery, School of Life and Health Sciences, The Chinese University of Hong Kong, Shenzhen, China.
  • Xie XJ; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Du Y; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Lee CS; Kobilka Institute of Innovative Drug Discovery, School of Life and Health Sciences, The Chinese University of Hong Kong, Shenzhen, China.
  • Lee HC; Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
  • Zhang H; State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen, China.
  • Zhao YJ; Department of Biology, Southern University of Science and Technology, Shenzhen, China.
Elife ; 102021 05 04.
Article en En | MEDLINE | ID: mdl-33944777
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas del Citoesqueleto / Evaluación Preclínica de Medicamentos / Proteínas del Dominio Armadillo / Colorantes Fluorescentes / Neuroprotección Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteínas del Citoesqueleto / Evaluación Preclínica de Medicamentos / Proteínas del Dominio Armadillo / Colorantes Fluorescentes / Neuroprotección Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article