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Repeated infusion of mesenchymal stem cells maintain the condition to inhibit deteriorated motor function, leading to an extended lifespan in the SOD1G93A rat model of amyotrophic lateral sclerosis.
Magota, Hirotoshi; Sasaki, Masanori; Kataoka-Sasaki, Yuko; Oka, Shinichi; Ukai, Ryo; Kiyose, Ryo; Onodera, Rie; Kocsis, Jeffery D; Honmou, Osamu.
  • Magota H; Department of Neural Regenerative Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8556, Japan.
  • Sasaki M; Tominaga Hospital, Naniwa-ku, Osaka-shi, Osaka, 556-0017, Japan.
  • Kataoka-Sasaki Y; Department of Neural Regenerative Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8556, Japan. msasaki@sapmed.ac.jp.
  • Oka S; Department of Neurology, Yale University School of Medicine, New Haven, CT, 06510, USA. msasaki@sapmed.ac.jp.
  • Ukai R; Center for Neuroscience and Regeneration Research, VA Connecticut Healthcare System, West Haven, CT, 06516, USA. msasaki@sapmed.ac.jp.
  • Kiyose R; Department of Neural Regenerative Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8556, Japan.
  • Onodera R; Department of Neural Regenerative Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8556, Japan.
  • Kocsis JD; Department of Neural Regenerative Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8556, Japan.
  • Honmou O; Department of Neural Regenerative Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Hokkaido, 060-8556, Japan.
Mol Brain ; 14(1): 76, 2021 05 07.
Article en En | MEDLINE | ID: mdl-33962678
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trasplante de Células Madre Mesenquimatosas / Células Madre Mesenquimatosas / Superóxido Dismutasa-1 / Esclerosis Amiotrófica Lateral / Longevidad / Neuronas Motoras Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Trasplante de Células Madre Mesenquimatosas / Células Madre Mesenquimatosas / Superóxido Dismutasa-1 / Esclerosis Amiotrófica Lateral / Longevidad / Neuronas Motoras Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article