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Macrocyclic peptides exhibit antiviral effects against influenza virus HA and prevent pneumonia in animal models.
Saito, Makoto; Itoh, Yasushi; Yasui, Fumihiko; Munakata, Tsubasa; Yamane, Daisuke; Ozawa, Makoto; Ito, Risa; Katoh, Takayuki; Ishigaki, Hirohito; Nakayama, Misako; Shichinohe, Shintaro; Yamaji, Kenzaburo; Yamamoto, Naoki; Ikejiri, Ai; Honda, Tomoko; Sanada, Takahiro; Sakoda, Yoshihiro; Kida, Hiroshi; Le, Thi Quynh Mai; Kawaoka, Yoshihiro; Ogasawara, Kazumasa; Tsukiyama-Kohara, Kyoko; Suga, Hiroaki; Kohara, Michinori.
  • Saito M; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan.
  • Itoh Y; Division of Pathogenesis and Disease Regulation, Department of Pathology, Shiga University of Medical Science, Setatsukinowa, Otsu, Shiga, Japan.
  • Yasui F; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan.
  • Munakata T; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan.
  • Yamane D; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan.
  • Ozawa M; Transboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan.
  • Ito R; Department of Chemistry, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
  • Katoh T; Department of Chemistry, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan.
  • Ishigaki H; Division of Pathogenesis and Disease Regulation, Department of Pathology, Shiga University of Medical Science, Setatsukinowa, Otsu, Shiga, Japan.
  • Nakayama M; Division of Pathogenesis and Disease Regulation, Department of Pathology, Shiga University of Medical Science, Setatsukinowa, Otsu, Shiga, Japan.
  • Shichinohe S; Division of Pathogenesis and Disease Regulation, Department of Pathology, Shiga University of Medical Science, Setatsukinowa, Otsu, Shiga, Japan.
  • Yamaji K; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan.
  • Yamamoto N; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan.
  • Ikejiri A; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan.
  • Honda T; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan.
  • Sanada T; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan.
  • Sakoda Y; Laboratory of Microbiology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
  • Kida H; Hokkaido University Research Center for Zoonosis Control, Sapporo, Japan.
  • Le TQM; National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
  • Kawaoka Y; Division of Virology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
  • Ogasawara K; Division of Pathogenesis and Disease Regulation, Department of Pathology, Shiga University of Medical Science, Setatsukinowa, Otsu, Shiga, Japan.
  • Tsukiyama-Kohara K; Transboundary Animal Diseases Center, Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima, Japan. kkohara@vet.kagoshima-u.ac.jp.
  • Suga H; Department of Chemistry, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. hsuga@chem.s.u-tokyo.ac.jp.
  • Kohara M; Department of Microbiology and Cell Biology, Tokyo Metropolitan Institute of Medical Science, Setagaya-ku, Tokyo, Japan. kohara-mc@igakuken.or.jp.
Nat Commun ; 12(1): 2654, 2021 05 11.
Article en En | MEDLINE | ID: mdl-33976181

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Péptidos / Neumonía / Infecciones por Orthomyxoviridae / Glicoproteínas Hemaglutininas del Virus de la Influenza / Modelos Animales de Enfermedad / Subtipo H1N1 del Virus de la Influenza A Límite: Animals / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Antivirales / Péptidos / Neumonía / Infecciones por Orthomyxoviridae / Glicoproteínas Hemaglutininas del Virus de la Influenza / Modelos Animales de Enfermedad / Subtipo H1N1 del Virus de la Influenza A Límite: Animals / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article