Solitary castrate-resistant prostate cancer metastasis to adrenal gland with concordant intense avidity on PSMA and FDG PET.

McGeorge, Stephen; Phillips, Reece; Rukin, Nicholas J; Reynolds, Jamie; Roberts, Matthew J.

McGeorge S; Department of Urology, Royal Brisbane and Women's Hospital, Butterfield St, Herston, Queensland, 4029, Australia.
Phillips R; Faculty of Medicine, The University of Queensland, Herston, Queensland, 4006, Australia.
Rukin NJ; Department of Urology, Redcliffe Hospital, Anzac Avenue, Redcliffe, Queensland, 4020, Australia.
Reynolds J; Faculty of Medicine, The University of Queensland, Herston, Queensland, 4006, Australia.
Roberts MJ; Department of Urology, Redcliffe Hospital, Anzac Avenue, Redcliffe, Queensland, 4020, Australia.

Urol Case Rep ; 38: 101696, 2021 Sep.

Article en En | MEDLINE | ID: mdl-34007790

ABSTRACT

Isolated prostate cancer metastasis to the adrenal gland is rare. We report a case of concordant high uptake in a solitary adrenal metastasis on both prostate-specific membrane antigen and fluorodeoxyglucose positron-emission tomography in a patient with castrate-resistant prostate cancer. Good initial biochemical response was achieved with laparoscopic adrenalectomy. The patient developed lymph node recurrence 12 months later, although remains asymptomatic on hormonal treatment 22 months post-operatively, in keeping with prior results for metastasis-directed therapy which can delay time to additional treatment. Application of dual tracer PET can be valuable for prostate cancer staging and guidance of metastasis-directed treatment.

Palabras clave

Adrenalectomy; FDG; Fluorodeoxyglucose; PSMA; Prostate cancer; Prostate specific membrane antigen