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DDX17 is involved in DNA damage repair and modifies FUS toxicity in an RGG-domain dependent manner.
Fortuna, Tyler R; Kour, Sukhleen; Anderson, Eric N; Ward, Caroline; Rajasundaram, Dhivyaa; Donnelly, Christopher J; Hermann, Andreas; Wyne, Hala; Shewmaker, Frank; Pandey, Udai Bhan.
  • Fortuna TR; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Kour S; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Anderson EN; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Ward C; Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Rajasundaram D; Division of Health Informatics, Department of Pediatrics, Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Donnelly CJ; LiveLikeLou Center for ALS Research, Brain Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Hermann A; Department of Neurobiology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
  • Wyne H; Translational Neurodegeneration Section "Albrecht-Kossel", Department of Neurology, University Medical Center, University of Rostock, 18147, Rostock, Germany.
  • Shewmaker F; German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, 18147, Rostock, Germany.
  • Pandey UB; Center for Transdisciplinary Neurosciences Rostock (CTNR), University Medical Center, University of Rostock, 18147, Rostock, Germany.
Acta Neuropathol ; 142(3): 515-536, 2021 09.
Article en En | MEDLINE | ID: mdl-34061233

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteína FUS de Unión a ARN / Reparación del ADN / ARN Helicasas DEAD-box / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteína FUS de Unión a ARN / Reparación del ADN / ARN Helicasas DEAD-box / Esclerosis Amiotrófica Lateral Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans / Male Idioma: En Año: 2021 Tipo del documento: Article