Methyl CpG binding protein 2 promotes colorectal cancer metastasis by regulating N<sup>6</sup> -methyladenosine methylation through methyltransferase-like 14.

Wang, Shuo; Gan, Meifu; Chen, Chaoyi; Zhang, Yi; Kong, Jianlu; Zhang, Honghe; Lai, Maode

Methyl CpG binding protein 2 promotes colorectal cancer metastasis by regulating N⁶ -methyladenosine methylation through methyltransferase-like 14.

Wang, Shuo; Gan, Meifu; Chen, Chaoyi; Zhang, Yi; Kong, Jianlu; Zhang, Honghe; Lai, Maode.

Wang S; Department of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.
Gan M; Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Linhai, China.
Chen C; Department of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.
Zhang Y; Department of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.
Kong J; Department of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.
Zhang H; Department of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.
Lai M; Department of Pathology, Key Laboratory of Disease Proteomics of Zhejiang Province, Research Unit of Intelligence Classification of Tumor Pathology and Precision Therapy, Chinese Academy of Medical Sciences (2019RU042), Zhejiang University School of Medicine, Hangzhou, China.

Cancer Sci ; 112(8): 3243-3254, 2021 Aug.

Article en En | MEDLINE | ID: mdl-34097350

Asunto(s)

Adenosina/análogos & derivados; Neoplasias Colorrectales/metabolismo; Factores de Transcripción de Tipo Kruppel/genética; Proteína 2 de Unión a Metil-CpG/metabolismo; Metiltransferasas/genética; Regulación hacia Arriba; Adenosina/metabolismo; Animales; Línea Celular Tumoral; Neoplasias Colorrectales/genética; Progresión de la Enfermedad; Regulación Neoplásica de la Expresión Génica; Células HCT116; Células HT29; Humanos; Factor 4 Similar a Kruppel; Ratones; Trasplante de Neoplasias; Estabilidad del ARN

Palabras clave

METTL14; MeCP2; colorectal cancer; m6A methylation; metastasis

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Colorrectales / Adenosina / Regulación hacia Arriba / Factores de Transcripción de Tipo Kruppel / Proteína 2 de Unión a Metil-CpG / Metiltransferasas Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article

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