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Deep learning boosts sensitivity of mass spectrometry-based immunopeptidomics.
Wilhelm, Mathias; Zolg, Daniel P; Graber, Michael; Gessulat, Siegfried; Schmidt, Tobias; Schnatbaum, Karsten; Schwencke-Westphal, Celina; Seifert, Philipp; de Andrade Krätzig, Niklas; Zerweck, Johannes; Knaute, Tobias; Bräunlein, Eva; Samaras, Patroklos; Lautenbacher, Ludwig; Klaeger, Susan; Wenschuh, Holger; Rad, Roland; Delanghe, Bernard; Huhmer, Andreas; Carr, Steven A; Clauser, Karl R; Krackhardt, Angela M; Reimer, Ulf; Kuster, Bernhard.
  • Wilhelm M; Computational Mass Spectrometry, Technical University of Munich (TUM), Freising, Germany. mathias.wilhelm@tum.de.
  • Zolg DP; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany. mathias.wilhelm@tum.de.
  • Graber M; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Gessulat S; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Schmidt T; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Schnatbaum K; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Schwencke-Westphal C; JPT Peptide Technologies GmbH, Berlin, Germany.
  • Seifert P; Klinik und Poliklinik für Innere Medizin III, Klinikum rechts der Isar, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
  • de Andrade Krätzig N; German Cancer Consortium (DKTK), partner site Munich; and German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Zerweck J; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.
  • Knaute T; Klinik und Poliklinik für Innere Medizin III, Klinikum rechts der Isar, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
  • Bräunlein E; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.
  • Samaras P; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.
  • Lautenbacher L; Institute of Molecular Oncology and Functional Genomics, TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.
  • Klaeger S; Klinik und Poliklinik für Innere Medizin II, Klinikum rechts der Isar, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
  • Wenschuh H; JPT Peptide Technologies GmbH, Berlin, Germany.
  • Rad R; JPT Peptide Technologies GmbH, Berlin, Germany.
  • Delanghe B; Klinik und Poliklinik für Innere Medizin III, Klinikum rechts der Isar, School of Medicine, Technical University of Munich (TUM), Munich, Germany.
  • Huhmer A; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.
  • Carr SA; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Clauser KR; Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.
  • Krackhardt AM; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Reimer U; JPT Peptide Technologies GmbH, Berlin, Germany.
  • Kuster B; Center for Translational Cancer Research (TranslaTUM), TUM School of Medicine, Technical University of Munich (TUM), Munich, Germany.
Nat Commun ; 12(1): 3346, 2021 06 07.
Article en En | MEDLINE | ID: mdl-34099720

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Péptidos / Espectrometría de Masas en Tándem / Aprendizaje Profundo Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Péptidos / Espectrometría de Masas en Tándem / Aprendizaje Profundo Tipo de estudio: Diagnostic_studies / Prognostic_studies Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article