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Development of immunoprecipitation - two-dimensional liquid chromatography - mass spectrometry methodology as biomarker read-out to quantify phosphorylated tau in cerebrospinal fluid from Alzheimer disease patients.
Bijttebier, Sebastiaan; Theunis, Clara; Jahouh, Farid; Martins, Dina Rodrigues; Verhemeldonck, Marc; Grauwen, Karolien; Dillen, Lieve; Mercken, Marc.
  • Bijttebier S; DMPK, Janssen Pharmaceutica, Turnhoutseweg 30, Beerse, Belgium. Electronic address: sbijtteb@its.jnj.com.
  • Theunis C; R&D Neurosciences, Janssen Pharmaceutica, Turnhoutseweg 30, Beerse, Belgium. Electronic address: ctheuni3@its.jnj.com.
  • Jahouh F; DMPK, Janssen Pharmaceutica, Turnhoutseweg 30, Beerse, Belgium. Electronic address: fjahouh@ITS.JNJ.com.
  • Martins DR; R&D Neurosciences, Janssen Pharmaceutica, Turnhoutseweg 30, Beerse, Belgium. Electronic address: DRodri39@its.jnj.com.
  • Verhemeldonck M; DMPK, Janssen Pharmaceutica, Turnhoutseweg 30, Beerse, Belgium. Electronic address: MVERHEME@its.jnj.com.
  • Grauwen K; R&D Neurosciences, Janssen Pharmaceutica, Turnhoutseweg 30, Beerse, Belgium. Electronic address: kgrauwe@ITS.JNJ.com.
  • Dillen L; DMPK, Janssen Pharmaceutica, Turnhoutseweg 30, Beerse, Belgium. Electronic address: LDILLEN@its.jnj.com.
  • Mercken M; R&D Neurosciences, Janssen Pharmaceutica, Turnhoutseweg 30, Beerse, Belgium. Electronic address: MMERCKEN@its.jnj.com.
J Chromatogr A ; 1651: 462299, 2021 Aug 16.
Article en En | MEDLINE | ID: mdl-34107398
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Espectrometría de Masas / Biomarcadores / Proteínas tau / Inmunoprecipitación / Enfermedad de Alzheimer Tipo de estudio: Diagnostic_studies Límite: Aged / Animals / Humans / Middle aged Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Espectrometría de Masas / Biomarcadores / Proteínas tau / Inmunoprecipitación / Enfermedad de Alzheimer Tipo de estudio: Diagnostic_studies Límite: Aged / Animals / Humans / Middle aged Idioma: En Año: 2021 Tipo del documento: Article