Transcriptional Changes in CD16+ Monocytes May Contribute to the Pathogenesis of COVID-19.

Chilunda, Vanessa; Martinez-Aguado, Pablo; Xia, Li C; Cheney, Laura; Murphy, Aniella; Veksler, Veronica; Ruiz, Vanessa; Calderon, Tina M; Berman, Joan W

Chilunda, Vanessa; Martinez-Aguado, Pablo; Xia, Li C; Cheney, Laura; Murphy, Aniella; Veksler, Veronica; Ruiz, Vanessa; Calderon, Tina M; Berman, Joan W.

Chilunda V; Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, United States.
Martinez-Aguado P; Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, United States.
Xia LC; Department of Epidemiology and Public Health, Division of Biostatistics, Albert Einstein College of Medicine, Bronx, NY, United States.
Cheney L; Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, United States.
Murphy A; Department of Medicine, Division of Infectious Diseases, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY, United States.
Veksler V; Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, United States.
Ruiz V; Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, United States.
Calderon TM; Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, United States.
Berman JW; Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, United States.

Front Immunol ; 12: 665773, 2021.

Article en En | MEDLINE | ID: mdl-34108966

Asunto(s)

COVID-19/virología; Monocitos/virología; Receptores de IgG/metabolismo; SARS-CoV-2/patogenicidad; Transcripción Genética; Transcriptoma; Adulto; Anciano; Proteínas Reguladoras de la Apoptosis/genética; Proteínas Reguladoras de la Apoptosis/metabolismo; COVID-19/genética; COVID-19/inmunología; COVID-19/metabolismo; Estudios de Casos y Controles; Citocinas/genética; Citocinas/metabolismo; Femenino; Proteínas Ligadas a GPI/metabolismo; Perfilación de la Expresión Génica; Interacciones Huésped-Patógeno; Humanos; Mediadores de Inflamación/metabolismo; Factores Reguladores del Interferón/genética; Factores Reguladores del Interferón/metabolismo; Masculino; Persona de Mediana Edad; Proteínas Mitocondriales/genética; Proteínas Mitocondriales/metabolismo; Monocitos/inmunología; Monocitos/metabolismo; RNA-Seq; SARS-CoV-2/inmunología; Índice de Severidad de la Enfermedad; Análisis de la Célula Individual; Adulto Joven

Palabras clave

SARS-CoV-2; cell movement; inflammation; non-classical monocytes; single-cell transcriptomics

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Transcripción Genética / Monocitos / Receptores de IgG / Transcriptoma / SARS-CoV-2 / COVID-19 Tipo de estudio: Etiology_studies / Observational_studies Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article

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