A role for the Cockayne Syndrome B (CSB)-Elongin ubiquitin ligase complex in signal-dependent RNA polymerase II transcription.

Weems, Juston C; Slaughter, Brian D; Unruh, Jay R; Weaver, Kyle J; Miller, Brandon D; Delventhal, Kym M; Conaway, Joan W; Conaway, Ronald C

Weems, Juston C; Slaughter, Brian D; Unruh, Jay R; Weaver, Kyle J; Miller, Brandon D; Delventhal, Kym M; Conaway, Joan W; Conaway, Ronald C.

Weems JC; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Slaughter BD; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Unruh JR; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Weaver KJ; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Miller BD; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Delventhal KM; Stowers Institute for Medical Research, Kansas City, Missouri, USA.
Conaway JW; Stowers Institute for Medical Research, Kansas City, Missouri, USA; Department of Biochemistry & Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA. Electronic address: Joan.Conaway@UTSouthwestern.edu.
Conaway RC; Stowers Institute for Medical Research, Kansas City, Missouri, USA; Department of Biochemistry & Molecular Biology, University of Kansas Medical Center, Kansas City, Kansas, USA. Electronic address: rcc@stowers.org.

J Biol Chem ; 297(1): 100862, 2021 07.

Article en En | MEDLINE | ID: mdl-34116057

Asunto(s)

ADN Helicasas/genética; Enzimas Reparadoras del ADN/genética; Elonguina/genética; Proteínas de Unión a Poli-ADP-Ribosa/genética; ARN Polimerasa II/genética; Ubiquitina-Proteína Ligasas/genética; Animales; Síndrome de Cockayne/enzimología; Síndrome de Cockayne/genética; ADN Helicasas/química; ADN Helicasas/ultraestructura; Reparación del ADN/genética; Enzimas Reparadoras del ADN/química; Enzimas Reparadoras del ADN/ultraestructura; Elonguina/química; Elonguina/ultraestructura; Humanos; Ratones; Complejos Multiproteicos/química; Complejos Multiproteicos/genética; Complejos Multiproteicos/ultraestructura; Proteínas de Unión a Poli-ADP-Ribosa/química; Proteínas de Unión a Poli-ADP-Ribosa/ultraestructura; ARN Polimerasa II/química; Receptores de Glucocorticoides/química; Receptores de Glucocorticoides/genética; Ubiquitina/química; Ubiquitina/genética; Ubiquitina-Proteína Ligasas/química; Ubiquitina-Proteína Ligasas/ultraestructura; Ubiquitinación/genética

Palabras clave

Cockayne syndrome B (CSB); Elongin; RNA polymerase II; chromatin immunoprecipitation (ChIP); fluorescence resonance energy transfer (FRET); glucocorticoid receptor; transcription elongation factor; transcription regulation; ubiquitin ligase

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: ARN Polimerasa II / ADN Helicasas / Enzimas Reparadoras del ADN / Ubiquitina-Proteína Ligasas / Proteínas de Unión a Poli-ADP-Ribosa / Elonguina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article

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