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Integrated transcriptomic analysis of human tuberculosis granulomas and a biomimetic model identifies therapeutic targets.
Reichmann, Michaela T; Tezera, Liku B; Vallejo, Andres F; Vukmirovic, Milica; Xiao, Rui; Reynolds, James; Jogai, Sanjay; Wilson, Susan; Marshall, Ben; Jones, Mark G; Leslie, Alasdair; D'Armiento, Jeanine M; Kaminski, Naftali; Polak, Marta E; Elkington, Paul.
  • Reichmann MT; NIHR Biomedical Research Center, School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Tezera LB; NIHR Biomedical Research Center, School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Vallejo AF; Department of Infection and Immunity, University College London, London, United Kingdom.
  • Vukmirovic M; NIHR Biomedical Research Center, School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Xiao R; Firestone Institute for Respiratory Health-Division of Respirology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.
  • Reynolds J; Department of Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
  • Jogai S; Columbia University Medical Center, New York, New York, USA.
  • Wilson S; Ground Upwards Ltd, Winchester, United Kingdom.
  • Marshall B; NIHR Biomedical Research Center, School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Jones MG; NIHR Biomedical Research Center, School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Leslie A; NIHR Biomedical Research Center, School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • D'Armiento JM; NIHR Biomedical Research Center, School of Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
  • Kaminski N; Department of Infection and Immunity, University College London, London, United Kingdom.
  • Polak ME; Africa Health Research Institute, KwaZulu Natal, South Africa.
  • Elkington P; Columbia University Medical Center, New York, New York, USA.
J Clin Invest ; 131(15)2021 08 02.
Article en En | MEDLINE | ID: mdl-34128839
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tuberculosis Pulmonar / Granuloma del Sistema Respiratorio / RNA-Seq / Pulmón / Modelos Biológicos / Mycobacterium tuberculosis Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Tuberculosis Pulmonar / Granuloma del Sistema Respiratorio / RNA-Seq / Pulmón / Modelos Biológicos / Mycobacterium tuberculosis Límite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article