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Phase 1 Combination Study of the CHK1 Inhibitor Prexasertib and the PARP Inhibitor Olaparib in High-grade Serous Ovarian Cancer and Other Solid Tumors.
Do, Khanh T; Kochupurakkal, Bose; Kelland, Sarah; de Jonge, Adrienne; Hedglin, Jennifer; Powers, Allison; Quinn, Nicholas; Gannon, Courtney; Vuong, Loan; Parmar, Kalindi; Lazaro, Jean-Bernard; D'Andrea, Alan D; Shapiro, Geoffrey I.
  • Do KT; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. khanhdomd@gmail.com.
  • Kochupurakkal B; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Kelland S; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • de Jonge A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Hedglin J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Powers A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Quinn N; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Gannon C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Vuong L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Parmar K; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Lazaro JB; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • D'Andrea AD; Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
  • Shapiro GI; Center for DNA Damage and Repair, Dana-Farber Cancer Institute, Boston, Massachusetts.
Clin Cancer Res ; 27(17): 4710-4716, 2021 09 01.
Article en En | MEDLINE | ID: mdl-34131002
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ftalazinas / Piperazinas / Pirazinas / Pirazoles / Cistadenocarcinoma Seroso / Inhibidores de Proteínas Quinasas / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Neoplasias Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Ftalazinas / Piperazinas / Pirazinas / Pirazoles / Cistadenocarcinoma Seroso / Inhibidores de Proteínas Quinasas / Inhibidores de Poli(ADP-Ribosa) Polimerasas / Neoplasias Límite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Año: 2021 Tipo del documento: Article