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Enzymatic Tailoring in Luzopeptin Biosynthesis Involves Cytochrome P450-Mediated Carbon-Nitrogen Bond Desaturation for Hydrazone Formation.
Shi, Xinjie; Huang, Liming; Song, Kaihui; Zhao, Guiyun; Liu, Yu; Lv, Longxian; Du, Yi-Ling.
  • Shi X; Institute of Pharmaceutical Biotechnology and The First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China.
  • Huang L; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University, 310003, Hangzhou, China.
  • Song K; Institute of Pharmaceutical Biotechnology and The First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China.
  • Zhao G; Institute of Pharmaceutical Biotechnology and The First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China.
  • Liu Y; Institute of Pharmaceutical Biotechnology and The First Affiliated Hospital, Zhejiang University School of Medicine, 310058, Hangzhou, China.
  • Lv L; College of Life Sciences, Zhejiang University, 310058, Hangzhou, China.
  • Du YL; State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University, 310003, Hangzhou, China.
Angew Chem Int Ed Engl ; 60(36): 19821-19828, 2021 09 01.
Article en En | MEDLINE | ID: mdl-34180113

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carbono / Sistema Enzimático del Citocromo P-450 / Hidrazonas / Nitrógeno Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carbono / Sistema Enzimático del Citocromo P-450 / Hidrazonas / Nitrógeno Idioma: En Año: 2021 Tipo del documento: Article