A Preliminary Study Showing the Impact of Genetic and Dietary Factors on GC-MS-Based Plasma Metabolome of Patients with and without <i>PROX1</i>-Genetic Predisposition to T2DM up to 5 Years Prior to Prediabetes Appearance.

Mojsak, Patrycja; Miniewska, Katarzyna; Godlewski, Adrian; Adamska-Patruno, Edyta; Samczuk, Paulina; Rey-Stolle, Fernanda; Bauer, Witold; Barbas, Coral; Kretowski, Adam; Ciborowski, Michal

A Preliminary Study Showing the Impact of Genetic and Dietary Factors on GC-MS-Based Plasma Metabolome of Patients with and without PROX1-Genetic Predisposition to T2DM up to 5 Years Prior to Prediabetes Appearance.

Mojsak, Patrycja; Miniewska, Katarzyna; Godlewski, Adrian; Adamska-Patruno, Edyta; Samczuk, Paulina; Rey-Stolle, Fernanda; Bauer, Witold; Barbas, Coral; Kretowski, Adam; Ciborowski, Michal.

Mojsak P; Clinical Research Centre, Medical University of Bialystok, Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.
Miniewska K; Clinical Research Centre, Medical University of Bialystok, Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.
Godlewski A; Clinical Research Centre, Medical University of Bialystok, Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.
Adamska-Patruno E; Clinical Research Centre, Medical University of Bialystok, Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.
Samczuk P; Clinical Research Centre, Medical University of Bialystok, Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.
Rey-Stolle F; Centre for Metabolomics and Bioanalysis (CEMBIO), Department of Chemistry and Biochemistry, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte, 28660 Madrid, Spain.
Bauer W; Clinical Research Centre, Medical University of Bialystok, Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.
Barbas C; Centre for Metabolomics and Bioanalysis (CEMBIO), Department of Chemistry and Biochemistry, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Urbanización Montepríncipe, Boadilla del Monte, 28660 Madrid, Spain.
Kretowski A; Clinical Research Centre, Medical University of Bialystok, Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.
Ciborowski M; Department of Endocrinology, Diabetology and Internal Medicine, Medical University of Bialystok, Sklodowskiej-Curie 24A, 15-276 Bialystok, Poland.

Curr Issues Mol Biol ; 43(2): 513-528, 2021 Jun 29.

Article en En | MEDLINE | ID: mdl-34209638

Asunto(s)

Diabetes Mellitus Tipo 2/epidemiología; Diabetes Mellitus Tipo 2/etiología; Dieta; Susceptibilidad a Enfermedades; Proteínas de Homeodominio/genética; Estado Prediabético/epidemiología; Estado Prediabético/etiología; Proteínas Supresoras de Tumor/genética; Alelos; Biomarcadores; Diabetes Mellitus Tipo 2/diagnóstico; Cromatografía de Gases y Espectrometría de Masas; Predisposición Genética a la Enfermedad; Genotipo; Humanos; Metaboloma; Metabolómica/métodos; Polonia/epidemiología; Polimorfismo de Nucleótido Simple; Estado Prediabético/diagnóstico

Palabras clave

GCMS; NC/HC-meal intake; PROX1; T2DM; amino acids; carbohydrates; fatty acids; metabolomics; plasma; prediabetes

Texto completo

Imprimir

XML

PubMed Links

Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Estado Prediabético / Proteínas de Homeodominio / Proteínas Supresoras de Tumor / Diabetes Mellitus Tipo 2 / Dieta / Susceptibilidad a Enfermedades Tipo de estudio: Diagnostic_studies / Risk_factors_studies / Screening_studies Límite: Humans País como asunto: Europa Idioma: En Año: 2021 Tipo del documento: Article

Texto completo

Imprimir

XML

PubMed Links

Search on Google