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Metabolic Enzyme DLST Promotes Tumor Aggression and Reveals a Vulnerability to OXPHOS Inhibition in High-Risk Neuroblastoma.
Anderson, Nicole M; Qin, Xiaodan; Finan, Jennifer M; Lam, Andrew; Athoe, Jacob; Missiaen, Rindert; Skuli, Nicolas; Kennedy, Annie; Saini, Amandeep S; Tao, Ting; Zhu, Shizhen; Nissim, Itzhak; Look, A Thomas; Qing, Guoliang; Simon, M Celeste; Feng, Hui.
  • Anderson NM; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Qin X; Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Finan JM; Departments of Pharmacology and Medicine, Section of Hematology and Medical Oncology, The Center for Cancer Research, Boston University School of Medicine, Boston, Massachusetts.
  • Lam A; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Athoe J; Departments of Pharmacology and Medicine, Section of Hematology and Medical Oncology, The Center for Cancer Research, Boston University School of Medicine, Boston, Massachusetts.
  • Missiaen R; Departments of Pharmacology and Medicine, Section of Hematology and Medical Oncology, The Center for Cancer Research, Boston University School of Medicine, Boston, Massachusetts.
  • Skuli N; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Kennedy A; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Saini AS; Abramson Family Cancer Research Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.
  • Tao T; Departments of Pharmacology and Medicine, Section of Hematology and Medical Oncology, The Center for Cancer Research, Boston University School of Medicine, Boston, Massachusetts.
  • Zhu S; National Clinical Research Center for Child Health, National Children's Regional Medical Center, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
  • Nissim I; Cancer Center, Zhejiang University, Hangzhou, Zhejiang, China.
  • Look AT; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota.
  • Qing G; Division of Genetics and Metabolism, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
  • Simon MC; Department of Pediatrics, Biochemistry, and Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania.
  • Feng H; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
Cancer Res ; 81(17): 4417-4430, 2021 09 01.
Article en En | MEDLINE | ID: mdl-34233924
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosforilación Oxidativa / Neoplasias Encefálicas / Aciltransferasas / Neuroblastoma Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosforilación Oxidativa / Neoplasias Encefálicas / Aciltransferasas / Neuroblastoma Tipo de estudio: Etiology_studies / Prognostic_studies / Risk_factors_studies Límite: Animals / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article