TLR4 and TNFR1 blockade dampen M1 macrophage activation and shifts them towards an M2 phenotype.

Sawoo, Ritasha; Dey, Rajen; Ghosh, Rituparna; Bishayi, Biswadev

Sawoo, Ritasha; Dey, Rajen; Ghosh, Rituparna; Bishayi, Biswadev.

Sawoo R; Department of Physiology, Immunology Laboratory, University of Calcutta, University Colleges of Science and Technology, 92 APC Road, Calcutta, 700009, West Bengal, India.
Dey R; Department of Physiology, Immunology Laboratory, University of Calcutta, University Colleges of Science and Technology, 92 APC Road, Calcutta, 700009, West Bengal, India.
Ghosh R; Department of Physiology, Immunology Laboratory, University of Calcutta, University Colleges of Science and Technology, 92 APC Road, Calcutta, 700009, West Bengal, India.
Bishayi B; Department of Physiology, Immunology Laboratory, University of Calcutta, University Colleges of Science and Technology, 92 APC Road, Calcutta, 700009, West Bengal, India. biswadevbishayi4@gmail.com.

Immunol Res ; 69(4): 334-351, 2021 08.

Article en En | MEDLINE | ID: mdl-34235623

Asunto(s)

Anticuerpos Neutralizantes/farmacología; Macrófagos Peritoneales/efectos de los fármacos; Receptores Inmunológicos/antagonistas & inhibidores; Animales; Arginasa/metabolismo; Radicales Libres/metabolismo; Glutatión/metabolismo; Interleucina-1beta/metabolismo; Lipopolisacáridos; Activación de Macrófagos/efectos de los fármacos; Macrófagos Peritoneales/metabolismo; Masculino; Ratones; Oxidorreductasas/metabolismo; Fenotipo; Receptores Inmunológicos/metabolismo; Factor de Necrosis Tumoral alfa/metabolismo

Palabras clave

Inflammation; LPS; M1/M2 polarization; Macrophage; TLR4; TNFR1

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores Inmunológicos / Macrófagos Peritoneales / Anticuerpos Neutralizantes Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article

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