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Hypoimmune induced pluripotent stem cell-derived cell therapeutics treat cardiovascular and pulmonary diseases in immunocompetent allogeneic mice.
Deuse, Tobias; Tediashvili, Grigol; Hu, Xiaomeng; Gravina, Alessia; Tamenang, Annika; Wang, Dong; Connolly, Andrew; Mueller, Christian; Mallavia, Beñat; Looney, Mark R; Alawi, Malik; Lanier, Lewis L; Schrepfer, Sonja.
  • Deuse T; Division of Cardiothoracic Surgery, Department of Surgery, Transplant and Stem Cell Immunobiology Laboratory, University of California, San Francisco, CA 94143.
  • Tediashvili G; Division of Cardiothoracic Surgery, Department of Surgery, Transplant and Stem Cell Immunobiology Laboratory, University of California, San Francisco, CA 94143.
  • Hu X; Department of Cardiovascular Surgery, University Heart Center Hamburg, 20246 Hamburg, Germany.
  • Gravina A; Division of Cardiothoracic Surgery, Department of Surgery, Transplant and Stem Cell Immunobiology Laboratory, University of California, San Francisco, CA 94143.
  • Tamenang A; Department of Cardiovascular Surgery, University Heart Center Hamburg, 20246 Hamburg, Germany.
  • Wang D; German Center for Cardiovascular Research (DZHK) partner site Hamburg/Kiel/Luebeck, 20246 Hamburg, Germany.
  • Connolly A; Sana Biotechnology Inc., South San Francisco, CA 94080.
  • Mueller C; Division of Cardiothoracic Surgery, Department of Surgery, Transplant and Stem Cell Immunobiology Laboratory, University of California, San Francisco, CA 94143.
  • Mallavia B; Division of Cardiothoracic Surgery, Department of Surgery, Transplant and Stem Cell Immunobiology Laboratory, University of California, San Francisco, CA 94143.
  • Looney MR; Department of Cardiovascular Surgery, University Heart Center Hamburg, 20246 Hamburg, Germany.
  • Alawi M; Division of Cardiothoracic Surgery, Department of Surgery, Transplant and Stem Cell Immunobiology Laboratory, University of California, San Francisco, CA 94143.
  • Lanier LL; Department of Pathology, University of California, San Francisco, CA 94143.
  • Schrepfer S; Horae Gene Therapy Center, University of Massachusetts, Worcester, MA 01605.
Proc Natl Acad Sci U S A ; 118(28)2021 07 13.
Article en En | MEDLINE | ID: mdl-34244428
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Trasplante de Células Madre / Células Madre Pluripotentes Inducidas / Inmunocompetencia / Enfermedades Pulmonares Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Enfermedades Cardiovasculares / Trasplante de Células Madre / Células Madre Pluripotentes Inducidas / Inmunocompetencia / Enfermedades Pulmonares Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article