Long Noncoding RNA <i>Tug1</i> Promotes Angiotensin II-Induced Renal Fibrosis by Binding to Mineralocorticoid Receptor and Negatively Regulating MicroR-29b-3p.

Zhang, Juhong; Zhang, Yuqing; Gao, Jing; Wang, Meihui; Li, Xiaoting; Cui, Zhaoqiang; Fu, Guosheng

Long Noncoding RNA Tug1 Promotes Angiotensin II-Induced Renal Fibrosis by Binding to Mineralocorticoid Receptor and Negatively Regulating MicroR-29b-3p.

Zhang, Juhong; Zhang, Yuqing; Gao, Jing; Wang, Meihui; Li, Xiaoting; Cui, Zhaoqiang; Fu, Guosheng.

Zhang J; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, Hangzhou, China (J.Z., J.G., M.W., X.L., G.F.).
Zhang Y; Department of Cardiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, China (Y.Z.).
Gao J; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, Hangzhou, China (J.Z., J.G., M.W., X.L., G.F.).
Wang M; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, Hangzhou, China (J.Z., J.G., M.W., X.L., G.F.).
Li X; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, Hangzhou, China (J.Z., J.G., M.W., X.L., G.F.).
Cui Z; Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China (Z.C.).
Fu G; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University, Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, Hangzhou, China (J.Z., J.G., M.W., X.L., G.F.).

Hypertension ; 78(3): 693-705, 2021 09.

Article en En | MEDLINE | ID: mdl-34333990

Asunto(s)

Angiotensina II/farmacología; Enfermedades Renales/metabolismo; Riñón/metabolismo; MicroARNs/metabolismo; ARN Largo no Codificante/metabolismo; Receptores de Mineralocorticoides/metabolismo; Línea Celular; Fibrosis/genética; Fibrosis/metabolismo; Fibrosis/patología; Regulación de la Expresión Génica/efectos de los fármacos; Humanos; Riñón/efectos de los fármacos; Riñón/patología; Enfermedades Renales/genética; Enfermedades Renales/patología; MicroARNs/genética; ARN Largo no Codificante/genética; Receptores de Mineralocorticoides/genética

Palabras clave

aldosterone; angiotensin; fibrosis; gene expression; mineralocorticoids

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Angiotensina II / Receptores de Mineralocorticoides / MicroARNs / ARN Largo no Codificante / Riñón / Enfermedades Renales Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article

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