Assessing an intervention to improve the safety of automatic stop orders for inpatient antimicrobials.
Infect Prev Pract
; 2(2): 100062, 2020 Jun.
Article
en En
| MEDLINE
| ID: mdl-34368705
ABSTRACT
BACKGROUND:
Automatic stop orders (ASOs) for antimicrobials have been recommended as a component of antimicrobial stewardship programs, but may result in unintentional treatment interruption due to failure of providers to re-order an antimicrobial medication. We examined the impact of a multifaceted intervention designed to reduce the potential harms of interrupting antimicrobial treatment due to ASOs.METHODS:
An intervention was implemented that included pharmacist review of expiring antimicrobials as well as provider education to encourage use of a long-term antimicrobial order set for commonly used prophylactic antimicrobials. Pharmacist interventions and antimicrobial re-ordering was recorded. Percent of missed doses of a commonly used prophylactic antimicrobial, single strength co-trimoxazole, was compared pre- and post-intervention using a chi-squared test.RESULTS:
From November 1, 2015 to November 30, 2016, there were 401 individual pharmacist interventions for antimicrobial ASOs, resulting in 295 instances of antimicrobial re-ordering. The total percent of presumed missed single strength co-trimoxazole doses was reduced from 8.4% to 6.2% post-intervention (P<0.001).CONCLUSIONS:
This study found that a targeted intervention was associated with a reduction in unintended antimicrobial treatment interruption related to ASOs.
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MEDLINE
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En
Año:
2020
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Article