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DHES0815A, a novel antibody-drug conjugate targeting HER2/neu, is highly active against uterine serous carcinomas in vitro and in vivo.
Tymon-Rosario, Joan; Bonazzoli, Elena; Bellone, Stefania; Manzano, Aranzazu; Pelligra, Silvia; Guglielmi, Adele; Gnutti, Barbara; Nagarkatti, Nupur; Zeybek, Burak; Manara, Paola; Zammataro, Luca; Harold, Justin; Mauricio, Dennis; Buza, Natalia; Hui, Pei; Altwerger, Gary; Menderes, Gulden; Ratner, Elena; Clark, Mitchell; Andikyan, Vaagn; Huang, Gloria S; Silasi, Dan-Arin; Azodi, Masoud; Schwartz, Peter E; Santin, Alessandro D.
  • Tymon-Rosario J; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Bonazzoli E; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Bellone S; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Manzano A; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Pelligra S; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA; Gynecologic Oncology Unit, Women Wealth Area, Department of Woman and Child Health and Public Health, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, Rome, Italy.
  • Guglielmi A; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Gnutti B; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Nagarkatti N; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Zeybek B; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Manara P; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Zammataro L; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Harold J; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Mauricio D; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Buza N; Department of Pathology, Yale University School of Medicine, CT 06520, USA.
  • Hui P; Department of Pathology, Yale University School of Medicine, CT 06520, USA.
  • Altwerger G; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Menderes G; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Ratner E; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Clark M; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Andikyan V; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Huang GS; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Silasi DA; Gynecologic Oncology, Obstetrics and Gynecology, Mercy Hospital St. Louis, MO 63141, USA.
  • Azodi M; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Schwartz PE; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA.
  • Santin AD; Department of Obstetrics, Gynecology, Reproductive Sciences Yale University School of Medicine, CT 06520, USA. Electronic address: alessandro.santin@yale.edu.
Gynecol Oncol ; 163(2): 334-341, 2021 11.
Article en En | MEDLINE | ID: mdl-34452746
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Uterinas / Benzodiazepinas / Cistadenocarcinoma Seroso / Receptor ErbB-2 / Inmunoconjugados / Anticuerpos Monoclonales Humanizados Límite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Uterinas / Benzodiazepinas / Cistadenocarcinoma Seroso / Receptor ErbB-2 / Inmunoconjugados / Anticuerpos Monoclonales Humanizados Límite: Adult / Aged / Aged80 / Female / Humans / Middle aged Idioma: En Año: 2021 Tipo del documento: Article