Pepsin pretreatment corrects underestimation of 25-hydroxyvitamin D measurement by an automated immunoassay in subjects with high vitamin D binding protein levels.

Muller Kobold, Anneke C; Kema, Ido P; Dijck-Brouwer, Janneke; Koerts, Karin; Weening, Michiel; Storteboom, Twan; Kootstra-Ros, Jenny E; van Faassen, Martijn; Riphagen, Ineke J

Muller Kobold, Anneke C; Kema, Ido P; Dijck-Brouwer, Janneke; Koerts, Karin; Weening, Michiel; Storteboom, Twan; Kootstra-Ros, Jenny E; van Faassen, Martijn; Riphagen, Ineke J.

Muller Kobold AC; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Kema IP; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Dijck-Brouwer J; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Koerts K; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Weening M; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Storteboom T; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Kootstra-Ros JE; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
van Faassen M; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Riphagen IJ; Department of Laboratory Medicine, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

Clin Chem Lab Med ; 60(1): e18-e20, 2022 01 26.

Article en En | MEDLINE | ID: mdl-34464525

Asunto(s)

Pepsina A; Proteína de Unión a Vitamina D; 25-Hidroxivitamina D 2; Humanos; Inmunoensayo; Pepsina A/metabolismo; Vitamina D/análogos & derivados; Vitamina D/metabolismo

Palabras clave

immunoassay; liquid chromatography-tandem mass spectrometry (LC-MS/MS); pepsin digestion; vitamin D; vitamin D-binding protein (VDBP)

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteína de Unión a Vitamina D / Pepsina A Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Proteína de Unión a Vitamina D / Pepsina A Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article