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Inhibiting Focal Adhesion Kinase Ameliorates Cyst Development in Polycystin-1-Deficient Polycystic Kidney Disease in Animal Model.
He, Jinzhao; Zhang, Shun; Qiu, Zhiwei; Li, Xiaowei; Huang, Huihui; Jin, William; Xu, Yue; Shao, Guangying; Wang, Liang; Meng, Jia; Wang, Shuyuan; Geng, Xiaoqiang; Jia, Yingli; Li, Min; Yang, Baoxue; Jenny Lu, Hua A; Zhou, Hong.
  • He J; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Zhang S; Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
  • Qiu Z; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Li X; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Huang H; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Jin W; Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
  • Xu Y; Harvard Medical School, Boston, Massachusetts.
  • Shao G; Division of Graduate Medical Sciences, Boston University School of Medicine, Boston, Massachusetts.
  • Wang L; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Meng J; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Wang S; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Geng X; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Jia Y; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Li M; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Yang B; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Jenny Lu HA; State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, China.
  • Zhou H; Key Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China.
J Am Soc Nephrol ; 32(9): 2159-2174, 2021 09.
Article en En | MEDLINE | ID: mdl-34465607
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Sulfonamidas / Benzamidas / Riñón Poliquístico Autosómico Dominante / Células Epiteliales / Proteína-Tirosina Quinasas de Adhesión Focal / Aminopiridinas / Ácidos Hidroxámicos Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pirazinas / Sulfonamidas / Benzamidas / Riñón Poliquístico Autosómico Dominante / Células Epiteliales / Proteína-Tirosina Quinasas de Adhesión Focal / Aminopiridinas / Ácidos Hidroxámicos Tipo de estudio: Etiology_studies Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article