Mesenchymal Stem Cell-Conditioned Media Regulate Steroidogenesis and Inhibit Androgen Secretion in a PCOS Cell Model via BMP-2.

Chugh, Rishi Man; Park, Hang-Soo; Esfandyari, Sahar; Elsharoud, Amro; Ulin, Mara; Al-Hendy, Ayman

Chugh, Rishi Man; Park, Hang-Soo; Esfandyari, Sahar; Elsharoud, Amro; Ulin, Mara; Al-Hendy, Ayman.

Chugh RM; Department of Surgery, University of Illinois at Chicago, 820 South Wood Street, Chicago, IL 60612, USA.
Park HS; Department of Radiation Oncology, University of Kansas Medical Center, Kansas City, KS 66160, USA.
Esfandyari S; Department of Obstetrics and Gynecology, University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.
Elsharoud A; Department of Surgery, University of Illinois at Chicago, 820 South Wood Street, Chicago, IL 60612, USA.
Ulin M; Department of Surgery, University of Illinois at Chicago, 820 South Wood Street, Chicago, IL 60612, USA.
Al-Hendy A; Department of Surgery, University of Illinois at Chicago, 820 South Wood Street, Chicago, IL 60612, USA.

Int J Mol Sci ; 22(17)2021 Aug 25.

Article en En | MEDLINE | ID: mdl-34502090

Asunto(s)

Andrógenos/metabolismo; Proteína Morfogenética Ósea 2/farmacología; Síndrome del Ovario Poliquístico/metabolismo; Células Tecales/metabolismo; Adulto; Animales; Línea Celular Tumoral; Proliferación Celular; Células Cultivadas; Medios de Cultivo Condicionados/farmacología; Exocitosis; Femenino; Humanos; Células Madre Mesenquimatosas/metabolismo; Ratones; Células Tecales/efectos de los fármacos; Células Tecales/fisiología

Palabras clave

bone morphogenetic protein; mesenchymal stem cells; polycystic ovary syndrome

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Síndrome del Ovario Poliquístico / Células Tecales / Proteína Morfogenética Ósea 2 / Andrógenos Límite: Adult / Animals / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article

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