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Synthesis of N-methylpyridine-chlorofuranformamide analogs as novel OPG up-regulators and inhibitors of RANKL-induced osteoclastogenesis.
Liu, Chao; Li, Yining; Sheng, Ren; Han, Xiaowan; Bao, Li; Wang, Chenyin; Wang, Weizhi; Jiang, Xinhai; Han, Jiangxue; Lei, Lijuan; Li, Ni; Zhang, Jing; Chen, Minghua; Li, Yan; Wu, Yexiang; Li, Shunwang; Ren, Yu; Xu, Yanni; Si, Shuyi.
  • Liu C; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Li Y; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Sheng R; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Han X; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Bao L; Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing, China. Electronic address: baoli611980@ccmu.edu.cn.
  • Wang C; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Wang W; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Jiang X; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Han J; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Lei L; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Li N; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Zhang J; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Chen M; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Li Y; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Wu Y; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Li S; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Ren Y; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China.
  • Xu Y; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China. Electronic address: xuyanniwe
  • Si S; NHC Key Laboratory of Biotechnology of Antibiotics, National Center for Screening Novel Microbial Drugs, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College (CAMS & PUMC), 1# Tiantan Xili, Beijing 100050, China. Electronic address: sisyimb@h
Bioorg Chem ; 116: 105361, 2021 11.
Article en En | MEDLINE | ID: mdl-34562672
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridinas / Ligando RANK / Osteoprotegerina / Formamidas / Furanos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Piridinas / Ligando RANK / Osteoprotegerina / Formamidas / Furanos Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article