Tackling PARP inhibitor resistance.

Fugger, Kasper; Hewitt, Graeme; West, Stephen C; Boulton, Simon J

Fugger, Kasper; Hewitt, Graeme; West, Stephen C; Boulton, Simon J.

Fugger K; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
Hewitt G; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK.
West SC; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK. Electronic address: stephen.west@crick.ac.uk.
Boulton SJ; The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK; Artios Pharma Ltd. B940, Babraham Research Campus, Cambridge, CB22 3FH, UK. Electronic address: simon.boulton@crick.ac.uk.

Trends Cancer ; 7(12): 1102-1118, 2021 12.

Article en En | MEDLINE | ID: mdl-34563478

Asunto(s)

Antineoplásicos; Neoplasias Ováricas; Antineoplásicos/uso terapéutico; Resistencia a Antineoplásicos; Femenino; Genes Supresores de Tumor; Recombinación Homóloga/genética; Humanos; Neoplasias Ováricas/tratamiento farmacológico; Inhibidores de Poli(ADP-Ribosa) Polimerasas/farmacología; Inhibidores de Poli(ADP-Ribosa) Polimerasas/uso terapéutico

Palabras clave

base excision repair; homologous recombination repair; nucleotide metabolism; poly(ADP-ribose) polymerase inhibitors; therapy resistance

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Neoplasias Ováricas / Antineoplásicos Límite: Female / Humans Idioma: En Año: 2021 Tipo del documento: Article

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