Zopfiellasins A-D, Two Pairs of Epimeric Cytochalasins from Kiwi-Associated Fungus Zopfiella sp. and Their Antibacterial Assessment.
Molecules
; 26(18)2021 Sep 16.
Article
en En
| MEDLINE
| ID: mdl-34577082
ABSTRACT
In our continuous search for antibacterial agents against Pseudomonas syringae pv. actinidiae (Psa) from kiwi-associated fungi, two pairs of epimeric cytochalasins, zopfiellasins A-D (1-4), were characterized from the fungus Zopfiella sp. The structures were established on the basis of spectroscopic data analysis, while the absolute configurations were determined by single-crystal X-ray diffraction. Compounds 1 and 3 exhibited antibacterial activity against Psa with MIC values of 25 and 50 µg/mL, respectively. This is the first report of anti-Psa activity of cytochalasin derivatives.
Palabras clave
Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Sordariales
/
Citocalasinas
/
Actinidia
/
Antibacterianos
Tipo de estudio:
Risk_factors_studies
Idioma:
En
Año:
2021
Tipo del documento:
Article