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IL-23 amplifies the epithelial-mesenchymal transition of mechanically conditioned alveolar epithelial cells in rheumatoid arthritis-associated interstitial lung disease through mTOR/S6 signaling.
Zhang, Chujie; Wang, Shaohua; Lau, Jessica; Roden, Anja C; Matteson, Eric L; Sun, Jie; Luo, Fengming; Tschumperlin, Daniel J; Vassallo, Robert.
  • Zhang C; Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
  • Wang S; Department of Respiratory and Critical Care Medicine, West China School of Medicine and West China Hospital, Sichuan University, Chengdu, China.
  • Lau J; Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
  • Roden AC; Pulmonary and Critical Care Medicine, The Vancouver Clinic, Vancouver, Washington.
  • Matteson EL; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
  • Sun J; Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
  • Luo F; Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
  • Tschumperlin DJ; Department of Immunology, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
  • Vassallo R; Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Rochester, Minnesota.
Am J Physiol Lung Cell Mol Physiol ; 321(6): L1006-L1022, 2021 12 01.
Article en En | MEDLINE | ID: mdl-34585990

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Enfermedades Pulmonares Intersticiales / Proteínas Quinasas S6 Ribosómicas / Interleucina-23 / Células Epiteliales Alveolares / Serina-Treonina Quinasas TOR / Transición Epitelial-Mesenquimal Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Artritis Reumatoide / Enfermedades Pulmonares Intersticiales / Proteínas Quinasas S6 Ribosómicas / Interleucina-23 / Células Epiteliales Alveolares / Serina-Treonina Quinasas TOR / Transición Epitelial-Mesenquimal Tipo de estudio: Etiology_studies / Risk_factors_studies Límite: Animals Idioma: En Año: 2021 Tipo del documento: Article