The Discovery of Peptide Macrocycle Rescuers of Pathogenic Protein Misfolding and Aggregation by Integrating SICLOPPS Technology and Ultrahigh-Throughput Screening in Bacteria.

Delivoria, Dafni C; Skretas, Georgios

Delivoria, Dafni C; Skretas, Georgios.

Delivoria DC; Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece.
Skretas G; Institute of Chemical Biology, National Hellenic Research Foundation, Athens, Greece. gskretas@eie.gr.

Methods Mol Biol ; 2371: 215-246, 2022.

Article en En | MEDLINE | ID: mdl-34596851

Asunto(s)

Pliegue de Proteína; Diabetes Mellitus Tipo 2; Escherichia coli/genética; Humanos; Péptidos; Péptidos Cíclicos; Proteínas; Tecnología

Palabras clave

Cyclic peptides; High-throughput screening; Protein aggregation; Protein misfolding diseases; SICLOPPS technology

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Pliegue de Proteína Tipo de estudio: Diagnostic_studies / Screening_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

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