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Generation of a control human induced pluripotent stem cell line using the defective and persistent Sendai virus vector system.
Zhou, Zhi; Yoshimatsu, Sho; Qian, Emi; Ishikawa, Mitsuru; Sato, Tsukika; Ohtaka, Manami; Nakanishi, Mahito; Okano, Hideyuki.
  • Zhou Z; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
  • Yoshimatsu S; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
  • Qian E; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
  • Ishikawa M; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
  • Sato T; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
  • Ohtaka M; National Institute of Advanced Industrial Science and Technology (AIST), Ibaraki, Japan; TOKIWA-Bio, Inc., Ibaraki, Japan.
  • Nakanishi M; National Institute of Advanced Industrial Science and Technology (AIST), Ibaraki, Japan; TOKIWA-Bio, Inc., Ibaraki, Japan.
  • Okano H; Department of Physiology, Keio University School of Medicine, Tokyo, Japan. Electronic address: hidokano@keio.jp.
Stem Cell Res ; 56: 102549, 2021 10.
Article en En | MEDLINE | ID: mdl-34598113
ABSTRACT
The defective and persistent Sendai virus (SeVdp) vector system allows efficient generation of transgene-free induced pluripotent stem cells (iPSCs) from human somatic cells. By leveraging the system, here we report the generation of an iPSC line from somatic fibroblasts of a healthy control donner (female), named KEIOi002-A (also named YG-iPS). The control iPSC line would be a useful resource for stem cell research and regenerative medicine.
Asunto(s)

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas Límite: Female / Humans Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Células Madre Pluripotentes Inducidas Límite: Female / Humans Idioma: En Año: 2021 Tipo del documento: Article