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Proton export alkalinizes intracellular pH and reprograms carbon metabolism to drive normal and malignant cell growth.
Man, Cheuk Him; Mercier, Francois E; Liu, Nian; Dong, Wentao; Stephanopoulos, Gregory; Jiang, Li; Jung, Yookyung; Lin, Charles P; Leung, Anskar Y H; Scadden, David T.
  • Man CH; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA.
  • Mercier FE; Center for Regenerative Medicine and Cancer Center, Massachusetts General Hospital, Boston, MA.
  • Liu N; Harvard Stem Cell Institute, Cambridge, MA.
  • Dong W; Ludwig Center, Harvard Medical School, Boston, MA.
  • Stephanopoulos G; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA.
  • Jiang L; Center for Regenerative Medicine and Cancer Center, Massachusetts General Hospital, Boston, MA.
  • Jung Y; Harvard Stem Cell Institute, Cambridge, MA.
  • Lin CP; Ludwig Center, Harvard Medical School, Boston, MA.
  • Leung AYH; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA.
  • Scadden DT; Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA.
Blood ; 139(4): 502-522, 2022 01 27.
Article en En | MEDLINE | ID: mdl-34610101
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carbono / Leucemia Mieloide Aguda / Ácido Láctico / Proliferación Celular Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carbono / Leucemia Mieloide Aguda / Ácido Láctico / Proliferación Celular Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article