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Inhibition of PIM Kinases in DLBCL Targets MYC Transcriptional Program and Augments the Efficacy of Anti-CD20 Antibodies.
Szydlowski, Maciej; Garbicz, Filip; Jablonska, Ewa; Górniak, Patryk; Komar, Dorota; Pyrzynska, Beata; Bojarczuk, Kamil; Prochorec-Sobieszek, Monika; Szumera-Cieckiewicz, Anna; Rymkiewicz, Grzegorz; Cybulska, Magdalena; Statkiewicz, Malgorzata; Gajewska, Marta; Mikula, Michal; Golas, Aniela; Domagala, Joanna; Winiarska, Magdalena; Graczyk-Jarzynka, Agnieszka; Bialopiotrowicz, Emilia; Polak, Anna; Barankiewicz, Joanna; Pula, Bartosz; Pawlak, Michal; Nowis, Dominika; Golab, Jakub; Tomirotti, Andrea M; Brzózka, Krzysztof; Pacheco-Blanco, Mariana; Kupcova, Kristyna; Green, Michael R; Havranek, Ondrej; Chapuy, Bjoern; Juszczynski, Przemyslaw.
  • Szydlowski M; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Garbicz F; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Jablonska E; Postgraduate School of Molecular Medicine, Medical University of Warsaw, Poland.
  • Górniak P; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Komar D; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Pyrzynska B; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Bojarczuk K; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.
  • Prochorec-Sobieszek M; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Szumera-Cieckiewicz A; Department of Hematology and Medical Oncology, University Medicine Göttingen, Göttingen, Germany.
  • Rymkiewicz G; Department of Diagnostic Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Cybulska M; Department of Diagnostic Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Statkiewicz M; Flow Cytometry Laboratory, Department of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Gajewska M; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Mikula M; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Golas A; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Domagala J; Department of Genetics, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland.
  • Winiarska M; Ryvu Therapeutics, Cracow, Poland.
  • Graczyk-Jarzynka A; Postgraduate School of Molecular Medicine, Medical University of Warsaw, Poland.
  • Bialopiotrowicz E; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.
  • Polak A; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.
  • Barankiewicz J; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.
  • Pula B; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Pawlak M; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Nowis D; Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Golab J; Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Tomirotti AM; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Brzózka K; Laboratory of Experimental Medicine, Medical University of Warsaw, Warsaw, Poland.
  • Pacheco-Blanco M; Department of Immunology, Medical University of Warsaw, Warsaw, Poland.
  • Kupcova K; Department of Experimental and Translational Oncology, Menarini Ricerche, Pomezia, Italy.
  • Green MR; Ryvu Therapeutics, Cracow, Poland.
  • Havranek O; BIOCEV, First Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Chapuy B; BIOCEV, First Faculty of Medicine, Charles University, Prague, Czech Republic.
  • Juszczynski P; Department of Lymphoma and Myeloma, University of Texas MD Anderson Cancer Center, Houston, Texas.
Cancer Res ; 81(23): 6029-6043, 2021 12 01.
Article en En | MEDLINE | ID: mdl-34625423
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / Proteínas Proto-Oncogénicas c-myc / Linfoma de Células B Grandes Difuso / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-pim-1 / Rituximab Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
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XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Regulación Neoplásica de la Expresión Génica / Proteínas Proto-Oncogénicas c-myc / Linfoma de Células B Grandes Difuso / Inhibidores de Proteínas Quinasas / Proteínas Proto-Oncogénicas c-pim-1 / Rituximab Tipo de estudio: Prognostic_studies Límite: Animals / Female / Humans Idioma: En Año: 2021 Tipo del documento: Article