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Rapamycin attenuates PLA2R activation-mediated podocyte apoptosis via the PI3K/AKT/mTOR pathway.
Chiou, Terry Ting-Yu; Chau, You-Ying; Chen, Jin-Bor; Hsu, Hsiang-Hao; Hung, Shao-Pei; Lee, Wen-Chin.
  • Chiou TT; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan; School of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan. Electronic address: cyang@cgmh.org.tw.
  • Chau YY; Centre for Cardiovascular Science, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh EH16 4TJ, UK. Electronic address: You-Ying.Chau@ed.ac.uk.
  • Chen JB; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan. Electronic address: jbchen@cgmh.org.tw.
  • Hsu HH; Kidney Research Center, Department of Nephrology, Linkou Chang Gung Memorial Hospital, Taoyuan 333423, Taiwan; College of Medicine, School of Medicine, Chang Gung University, Taoyuan 33302, Taiwan. Electronic address: hsianghao@cgmh.org.tw.
  • Hung SP; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan. Electronic address: helenhung@cgmh.org.tw.
  • Lee WC; Division of Nephrology, Department of Internal Medicine, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung 83301, Taiwan. Electronic address: leewc@cgmh.org.tw.
Biomed Pharmacother ; 144: 112349, 2021 Dec.
Article en En | MEDLINE | ID: mdl-34700229
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Glomerulonefritis Membranosa / Apoptosis / Sirolimus / Podocitos / Proteínas Proto-Oncogénicas c-akt / Receptores de Fosfolipasa A2 / Fosfatidilinositol 3-Quinasa / Serina-Treonina Quinasas TOR / Inhibidores mTOR Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Glomerulonefritis Membranosa / Apoptosis / Sirolimus / Podocitos / Proteínas Proto-Oncogénicas c-akt / Receptores de Fosfolipasa A2 / Fosfatidilinositol 3-Quinasa / Serina-Treonina Quinasas TOR / Inhibidores mTOR Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article