Acidic pH reduces agonist efficacy and responses to synaptic-like glycine applications in zebrafish &#945;1 and rat &#945;1ß recombinant glycine receptors.

Ivica, Josip; Lape, Remigijus; Sivilotti, Lucia G

Acidic pH reduces agonist efficacy and responses to synaptic-like glycine applications in zebrafish α1 and rat α1ß recombinant glycine receptors.

Ivica, Josip; Lape, Remigijus; Sivilotti, Lucia G.

Ivica J; Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK.
Lape R; Neurobiology Department, MRC Laboratory of Molecular Biology Cambridge Biomedical Campus Francis Crick Avenue, Cambridge, UK.
Sivilotti LG; Department of Neuroscience, Physiology and Pharmacology, University College London, London, UK.

J Physiol ; 600(2): 333-347, 2022 01.

Article en En | MEDLINE | ID: mdl-34802146

Asunto(s)

Glicina; Receptores de Glicina; Ácidos; Animales; Glicina/farmacología; Células HEK293; Humanos; Concentración de Iones de Hidrógeno; Técnicas de Placa-Clamp; Ratas; Pez Cebra

Palabras clave

glycine receptors; pH changes; single channel

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Receptores de Glicina / Glicina Tipo de estudio: Prognostic_studies Límite: Animals / Humans Idioma: En Año: 2022 Tipo del documento: Article

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