Impact of Tumor Suppressor Gene Co-Mutations on Differential Response to EGFR TKI Therapy in EGFR L858R and Exon 19 Deletion Lung Cancer.

Hellyer, Jessica A; White, Maya N; Gardner, Rebecca M; Cunanan, Kristen; Padda, Sukhmani K; Das, Millie; Ramchandran, Kavitha; Neal, Joel W; Wakelee, Heather A

Hellyer, Jessica A; White, Maya N; Gardner, Rebecca M; Cunanan, Kristen; Padda, Sukhmani K; Das, Millie; Ramchandran, Kavitha; Neal, Joel W; Wakelee, Heather A.

Hellyer JA; Stanford Cancer Institute/Stanford University School of Medicine, Stanford, CA.
White MN; Stanford Cancer Institute/Stanford University School of Medicine, Stanford, CA.
Gardner RM; Quantitative Sciences Unit, Stanford School of Medicine, Stanford, CA.
Cunanan K; Quantitative Sciences Unit, Stanford School of Medicine, Stanford, CA.
Padda SK; Stanford Cancer Institute/Stanford University School of Medicine, Stanford, CA.
Das M; Stanford Cancer Institute/Stanford University School of Medicine, Stanford, CA; Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA.
Ramchandran K; Stanford Cancer Institute/Stanford University School of Medicine, Stanford, CA.
Neal JW; Stanford Cancer Institute/Stanford University School of Medicine, Stanford, CA.
Wakelee HA; Stanford Cancer Institute/Stanford University School of Medicine, Stanford, CA. Electronic address: hwakelee@stanford.edu.

Clin Lung Cancer ; 23(3): 264-272, 2022 05.

Article en En | MEDLINE | ID: mdl-34838441

Asunto(s)

Carcinoma de Pulmón de Células no Pequeñas; Neoplasias Pulmonares; Carcinoma de Pulmón de Células no Pequeñas/tratamiento farmacológico; Carcinoma de Pulmón de Células no Pequeñas/genética; Receptores ErbB/genética; Exones/genética; Genes Supresores de Tumor; Humanos; Proteína 1 Asociada A ECH Tipo Kelch/genética; Neoplasias Pulmonares/tratamiento farmacológico; Neoplasias Pulmonares/genética; Mutación/genética; Factor 2 Relacionado con NF-E2/genética; Inhibidores de Proteínas Quinasas/farmacología; Inhibidores de Proteínas Quinasas/uso terapéutico; Estudios Retrospectivos

Palabras clave

Driver mutations; Gene interaction; NSCLC; Osimertinib; Targeted therapy

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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Carcinoma de Pulmón de Células no Pequeñas / Neoplasias Pulmonares Tipo de estudio: Observational_studies / Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Año: 2022 Tipo del documento: Article

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