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Structural and mechanistic basis of the high catalytic activity of monooxygenase Tet(X4) on tigecycline.
Cheng, Qipeng; Cheung, Yanchu; Liu, Chenyu; Xiao, Qingjie; Sun, Bo; Zhou, Jiahai; Chan, Edward Wai Chi; Zhang, Rong; Chen, Sheng.
  • Cheng Q; State Key Lab of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
  • Cheung Y; Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, Hong Kong.
  • Liu C; Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, Hong Kong.
  • Xiao Q; Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Kowloon, Hong Kong.
  • Sun B; Shanghai Advanced Research Institute, Chinese Academy of Sciences, No.239 Zhangheng Road, Shanghai, 201204, China.
  • Zhou J; Shanghai Advanced Research Institute, Chinese Academy of Sciences, No.239 Zhangheng Road, Shanghai, 201204, China.
  • Chan EWC; CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China.
  • Zhang R; State Key Lab of Chemical Biology and Drug Discovery, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
  • Chen S; Department of Clinical Laboratory, Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou, 310009, People's Republic of China.
BMC Biol ; 19(1): 262, 2021 12 11.
Article en En | MEDLINE | ID: mdl-34895224

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Escherichia coli / Oxigenasas de Función Mixta Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Escherichia coli / Oxigenasas de Función Mixta Idioma: En Año: 2021 Tipo del documento: Article