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The T-cell clonal response to SARS-CoV-2 vaccination in inflammatory bowel disease patients is augmented by anti-TNF therapy and often deficient in antibody-responders.
Li, Dalin; Xu, Alexander; Mengesha, Emebet; Elyanow, Rebecca; Gittelman, Rachel M; Chapman, Heidi; Prostko, John C; Frias, Edwin C; Stewart, James L; Pozdnyakova, Valeriya; Debbas, Philip; Mujukian, Angela; Horizon, Arash A; Merin, Noah; Joung, Sandy; Botwin, Gregory J; Sobhani, Kimia; Figueiredo, Jane C; Cheng, Susan; Kaplan, Ian M; McGovern, Dermot P B; Merchant, Akil; Melmed, Gil Y; Braun, Jonathan.
  • Li D; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Xu A; Cedars Sinai Cancer and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Mengesha E; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Elyanow R; Adaptive Biotechnologies, Seattle, WA, USA.
  • Gittelman RM; Adaptive Biotechnologies, Seattle, WA, USA.
  • Chapman H; Adaptive Biotechnologies, Seattle, WA, USA.
  • Prostko JC; Applied Research and Technology, Abbott Diagnostics, Abbott Park, IL.
  • Frias EC; Applied Research and Technology, Abbott Diagnostics, Abbott Park, IL.
  • Stewart JL; Applied Research and Technology, Abbott Diagnostics, Abbott Park, IL.
  • Pozdnyakova V; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Debbas P; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Mujukian A; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Horizon AA; Center for Rheumatology Medical Group, Los Angeles, CA, USA.
  • Merin N; Cedars Sinai Cancer and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Joung S; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Botwin GJ; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Sobhani K; Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Figueiredo JC; Cedars Sinai Cancer and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Cheng S; Department of Cardiology, Smidt Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Kaplan IM; Adaptive Biotechnologies, Seattle, WA, USA.
  • McGovern DPB; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Merchant A; Cedars Sinai Cancer and Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Melmed GY; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
  • Braun J; F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
medRxiv ; 2021 Dec 08.
Article en En | MEDLINE | ID: mdl-34909785