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Membrane-bound IL-6R is upregulated on Th17 cells and inhibits Treg cell migration by regulating post-translational modification of VASP in autoimmune arthritis.
Yan, Shuaifeng; Golumba-Nagy, Viktoria; Kotschenreuther, Konstantin; Thiele, Jan; Refaian, Nasrin; Shuya, Deng; Gloyer, Lydia; Dittrich-Salamon, Mara; Meyer, Anja; Heindl, Ludwig M; Kofler, David M.
  • Yan S; Laboratory of Molecular Immunology, Division of Rheumatology and Clinical Immunology, Department I of Internal Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany.
  • Golumba-Nagy V; Laboratory of Molecular Immunology, Division of Rheumatology and Clinical Immunology, Department I of Internal Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany.
  • Kotschenreuther K; Laboratory of Molecular Immunology, Division of Rheumatology and Clinical Immunology, Department I of Internal Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany.
  • Thiele J; Laboratory of Molecular Immunology, Division of Rheumatology and Clinical Immunology, Department I of Internal Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany.
  • Refaian N; Department of Ophthalmology, University of Cologne, Cologne, Germany.
  • Shuya D; Department of Ophthalmology, University of Cologne, Cologne, Germany.
  • Gloyer L; Laboratory of Molecular Immunology, Division of Rheumatology and Clinical Immunology, Department I of Internal Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany.
  • Dittrich-Salamon M; Laboratory of Molecular Immunology, Division of Rheumatology and Clinical Immunology, Department I of Internal Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany.
  • Meyer A; Laboratory of Molecular Immunology, Division of Rheumatology and Clinical Immunology, Department I of Internal Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany.
  • Heindl LM; Department of Ophthalmology, University of Cologne, Cologne, Germany.
  • Kofler DM; Laboratory of Molecular Immunology, Division of Rheumatology and Clinical Immunology, Department I of Internal Medicine, University of Cologne, Kerpenerstr. 62, 50937, Cologne, Germany. david.kofler@uk-koeln.de.
Cell Mol Life Sci ; 79(1): 3, 2021 Dec 16.
Article en En | MEDLINE | ID: mdl-34913099

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfoproteínas / Artritis Reumatoide / Moléculas de Adhesión Celular / Linfocitos T Reguladores / Receptores de Interleucina-6 / Células Th17 / Proteínas de Microfilamentos Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Fosfoproteínas / Artritis Reumatoide / Moléculas de Adhesión Celular / Linfocitos T Reguladores / Receptores de Interleucina-6 / Células Th17 / Proteínas de Microfilamentos Límite: Animals / Humans Idioma: En Año: 2021 Tipo del documento: Article