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Structural analysis of receptor binding domain mutations in SARS-CoV-2 variants of concern that modulate ACE2 and antibody binding.
Mannar, Dhiraj; Saville, James W; Zhu, Xing; Srivastava, Shanti S; Berezuk, Alison M; Zhou, Steven; Tuttle, Katharine S; Kim, Andrew; Li, Wei; Dimitrov, Dimiter S; Subramaniam, Sriram.
  • Mannar D; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Saville JW; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Zhu X; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Srivastava SS; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Berezuk AM; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Zhou S; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Tuttle KS; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
  • Kim A; Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, UPMC, 3550 Terrace Str, Pittsburgh, PA 15261, USA.
  • Li W; Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, UPMC, 3550 Terrace Str, Pittsburgh, PA 15261, USA.
  • Dimitrov DS; Center for Antibody Therapeutics, Division of Infectious Diseases, Department of Medicine, UPMC, 3550 Terrace Str, Pittsburgh, PA 15261, USA.
  • Subramaniam S; Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. Electronic address: sriram.subramaniam@ubc.ca.
Cell Rep ; 37(12): 110156, 2021 12 21.
Article en En | MEDLINE | ID: mdl-34914928
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Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Glicoproteína de la Espiga del Coronavirus / Enzima Convertidora de Angiotensina 2 / SARS-CoV-2 Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article
Texto completo
Imprimir
XML
PubMed Links
Search on Google

Texto completo: 1 Banco de datos: MEDLINE Asunto principal: Glicoproteína de la Espiga del Coronavirus / Enzima Convertidora de Angiotensina 2 / SARS-CoV-2 Límite: Humans Idioma: En Año: 2021 Tipo del documento: Article