Tautomerism troubles: proton transfer modifies the stereochemical assignments in diastereoisomeric structures of spiro-cyclic 5-methyl-2<i>H</i>-imidazol-4-amine dimers.

Blade, Helen; Horton, Peter N; Morrison, James A; Orton, James B; Sullivan, Rachel A; Coles, Simon J

Tautomerism troubles: proton transfer modifies the stereochemical assignments in diastereoisomeric structures of spiro-cyclic 5-methyl-2H-imidazol-4-amine dimers.

Blade, Helen; Horton, Peter N; Morrison, James A; Orton, James B; Sullivan, Rachel A; Coles, Simon J.

Blade H; AstraZeneca, Oral Product Development, Pharmaceutical Technology & Development, Operations, Macclesfield, United Kingdom.
Horton PN; School of Chemistry, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton, SO17 1BJ, United Kingdom.
Morrison JA; AstraZeneca, Chemical Development, Pharmaceutical Technology & Development, Operations, Macclesfield, United Kingdom.
Orton JB; School of Chemistry, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton, SO17 1BJ, United Kingdom.
Sullivan RA; AstraZeneca, Chemical Development, Pharmaceutical Technology & Development, Operations, Macclesfield, United Kingdom.
Coles SJ; School of Chemistry, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton, SO17 1BJ, United Kingdom.

Acta Crystallogr E Crystallogr Commun ; 77(Pt 12): 1311-1315, 2021 Dec 01.

Article en En | MEDLINE | ID: mdl-34925905