[In vivo study of the protective action of the splenocytes from CBA strain mice immunized with an inactivated nonconcentrated rabies vaccine]. / Izuchenie in vivo zashchitnogo deistviia splenotsitov myshei linii CBA, immunizirovannykh inaktivirovannoi nekontsentrirovannoi antirabicheskoi vaktsinoi.

ABSTRACT

An inactivated unconcentrated rabies vaccine was demonstrated to induce the production of T-killers which in adoptive transfer protect 38-43% of recipients challenged intramuscularly with street rabies virus. The production of T-killers depends on the dose and schedule of the antigen inoculation. T-killers in vivo were strictly specific and manifested their protective effect only in syngeneic but not in allogeneic system.