Rhodomollosides A and B, glycosides of methyl everninate from the aerial parts of Rhododendron molle.
J Asian Nat Prod Res
; 24(11): 1025-1032, 2022 Nov.
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| MEDLINE
| ID: mdl-34937451
ABSTRACT
Two new glycosides of methyl everninate, rhodomollosides A (1) and B (2), were isolated from the aerial parts of a medicinal plant Rhododendron molle. The structures of 1 and 2 were elucidated on the basis of detailed spectroscopic analyses as well as HPLC analyses for thiazolidine derivatives of their sugar moieties. The sugar moiety of rhodomolloside A (1) was elucidated to be a rare monosaccharide, D-allose, while rhodomolloside B (2) was assigned as a D-glucoside of methyl everninate. Furthermore, they were evaluated for their cytotoxicity against RAW264.7 cells, and for their inhibitory effects with a lipopolysaccharide (LPS)-stimulated murine macrophages RAW 264.7 cells model.
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Texto completo:
1
Banco de datos:
MEDLINE
Asunto principal:
Rhododendron
/
Diterpenos
Límite:
Animals
Idioma:
En
Año:
2022
Tipo del documento:
Article