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Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3.
Abbattista, Maria R; Ashoorzadeh, Amir; Guise, Christopher P; Mowday, Alexandra M; Mittra, Rituparna; Silva, Shevan; Hicks, Kevin O; Bull, Matthew R; Jackson-Patel, Victoria; Lin, Xiaojing; Prosser, Gareth A; Lambie, Neil K; Dachs, Gabi U; Ackerley, David F; Smaill, Jeff B; Patterson, Adam V.
  • Abbattista MR; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.
  • Ashoorzadeh A; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.
  • Guise CP; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand.
  • Mowday AM; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.
  • Mittra R; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.
  • Silva S; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand.
  • Hicks KO; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.
  • Bull MR; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.
  • Jackson-Patel V; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.
  • Lin X; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.
  • Prosser GA; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand.
  • Lambie NK; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.
  • Dachs GU; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand.
  • Ackerley DF; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.
  • Smaill JB; School of Biological Sciences, Victoria University of Wellington, Wellington 6011, New Zealand.
  • Patterson AV; School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK.
Pharmaceuticals (Basel) ; 14(12)2021 Nov 26.
Article en En | MEDLINE | ID: mdl-34959631

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Año: 2021 Tipo del documento: Article

Texto completo: 1 Banco de datos: MEDLINE Tipo de estudio: Prognostic_studies Idioma: En Año: 2021 Tipo del documento: Article